Unprecedented Diterpenoids as a PTP1B Inhibitor from the Hainan Soft Coral Sarcophyton trocheliophorum Marenzeller

Methyl sarcotroates A and B (3 and 4), two unprecedented diterpenoids possessing a tetradecahydrocyclopenta[3′,4′]cyclobuta[1′,2′:4,5]cyclonona[1,2-b]oxirene ring system, along with their probable biogenetic precursor, sarcophytonolide M (1), were isolated from the Hainan soft coral Sarcophyton troc...

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Veröffentlicht in:	Organic letters 2013-01, Vol.15 (2), p.274-277
Hauptverfasser:	Liang, Lin-Fu, Kurtán, Tibor, Mándi, Attila, Yao, Li-Gong, Li, Jia, Zhang, Wen, Guo, Yue-Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anthozoa - chemistry Diterpenes - chemistry Diterpenes - isolation & purification Diterpenes - pharmacology Drug Screening Assays, Antitumor Molecular Structure Nuclear Magnetic Resonance, Biomolecular Oleanolic Acid - pharmacology Protein Tyrosine Phosphatase, Non-Receptor Type 1 - antagonists & inhibitors
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