Function of BKCa Channels Is Reduced in Human Vascular Smooth Muscle Cells From Han Chinese Patients With Hypertension

Chronic hypertension is associated with an impaired vascular relaxation caused by an increased vascular tone; however, the underlying mechanisms are not fully understood in human patients. The present study was to investigate whether large-conductance Ca- and voltage-activated K (BKCa) channels are...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 2013-02, Vol.61 (2), p.519-525
Hauptverfasser:	Yang, Yan, Li, Peng-Yun, Cheng, Jun, Mao, Liang, Wen, Jing, Tan, Xiao-Qiu, Liu, Zhi-Fei, Zeng, Xiao-Rong
Format:	Artikel
Sprache:	eng
Schlagworte:	Arterial hypertension. Arterial hypotension Asian Continental Ancestry Group Biological and medical sciences Blood and lymphatic vessels Blood vessels and receptors Calcium - metabolism Cardiology. Vascular system China Fundamental and applied biological sciences. Psychology Humans Hypertension - metabolism Hypertension - physiopathology Large-Conductance Calcium-Activated Potassium Channels - metabolism Medical sciences Membrane Potentials - physiology Mesenteric Arteries - cytology Mesenteric Arteries - metabolism Mesenteric Arteries - physiopathology Muscle, Smooth, Vascular - cytology Muscle, Smooth, Vascular - metabolism Muscle, Smooth, Vascular - physiopathology Myocytes, Smooth Muscle - cytology Myocytes, Smooth Muscle - metabolism Vertebrates: cardiovascular system
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