Anticancer steroids: linking natural and semi-synthetic compounds
Steroids, a widespread class of natural organic compounds occurring in animals, plants and fungi, have shown great therapeutic value for a broad array of pathologies. The present overview is focused on the anticancer activity of steroids, which is very representative of a rich structural molecular d...
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| Veröffentlicht in: | Natural product reports 2013-01, Vol.30 (2), p.324-374 |
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| container_title | Natural product reports |
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| creator | Salvador, Jorge A R Carvalho, João F S Neves, Marco A C Silvestre, Samuel M Leitão, Alcino J Silva, M Manuel C Sá e Melo, M Luisa |
| description | Steroids, a widespread class of natural organic compounds occurring in animals, plants and fungi, have shown great therapeutic value for a broad array of pathologies. The present overview is focused on the anticancer activity of steroids, which is very representative of a rich structural molecular diversity and ability to interact with various biological targets and pathways. This review encompasses the most relevant discoveries on steroid anticancer drugs and leads through the last decade and comprises 668 references. |
| doi_str_mv | 10.1039/c2np20082a |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0265-0568 |
| ispartof | Natural product reports, 2013-01, Vol.30 (2), p.324-374 |
| issn | 0265-0568 1460-4752 |
| language | eng |
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| source | MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Animals Antineoplastic Agents - chemical synthesis Antineoplastic Agents - chemistry Antineoplastic Agents - isolation & purification Antineoplastic Agents - pharmacology Biological Products - chemical synthesis Biological Products - chemistry Biological Products - isolation & purification Biological Products - pharmacology Fungi Humans Molecular Structure Plants, Medicinal Steroids - chemical synthesis Steroids - chemistry Steroids - isolation & purification Steroids - pharmacology |
| title | Anticancer steroids: linking natural and semi-synthetic compounds |
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