Epithelial Barriers, Microbiota, and Colorectal Cancer

There is an established link between the inflammation process and the genesis of colorectal cancer. A recent study suggests that intestinal microbiota may have a mediatory role between the initial steps of tumorigenesis and the initiation of an immune response that influences clinical outcome. Color...

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Veröffentlicht in:	The New England journal of medicine 2013-01, Vol.368 (3), p.282-284
Hauptverfasser:	Gallimore, Awen M, Godkin, Andrew
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Physiological Phenomena Bacterial Translocation - genetics Bacterial Translocation - physiology Biological and medical sciences Colorectal cancer Colorectal Neoplasms - etiology Colorectal Neoplasms - genetics Colorectal Neoplasms - microbiology Cytotoxicity Diabetes Disease Epithelial Cells - physiology Gastroenterology. Liver. Pancreas. Abdomen General aspects Humans Inflammation - microbiology Interleukin-17 - immunology Interleukin-23 - immunology Medical sciences Metagenome Mutation Pathogenesis Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Th1 Cells - physiology Th17 Cells - physiology Tumors
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