Gastrokines: stomach-specific proteins with putative homeostatic and tumor suppressor roles

During the past decade, a new family of stomach-specific proteins has been recognized. Known as "gastrokines" (GKNs), these secreted proteins are products of gastric mucus-producing cell lineages. GKNs are highly conserved in physical structure, and emerging data point to convergent functi...

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Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2013-01, Vol.304 (2), p.G109-G121
Hauptverfasser:	Menheniott, Trevelyan R, Kurklu, Bayzar, Giraud, Andrew S
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Cells Crohn's disease Gastric cancer Gastrointestinal Hormones - chemistry Gastrointestinal Hormones - genetics Gastrointestinal Hormones - metabolism Homeostasis Humans Models, Molecular Molecular Sequence Data Peptides - metabolism Precancerous Conditions - genetics Precancerous Conditions - metabolism Precancerous Conditions - pathology Proteins Signal Transduction Stomach - metabolism Stomach - pathology Stomach Neoplasms - genetics Stomach Neoplasms - metabolism Stomach Neoplasms - pathology Stomach Neoplasms - prevention & control Trefoil Factor-2 Tumor Suppressor Proteins - metabolism Tumors Wound Healing
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