Idiopathic pulmonary haemosiderosis in a child with Down's syndrome: case report and review of the literature
We report the case of a female child with Down's syndrome affected by idiopathic pulmonary haemosiderosis (IPH), who was successfully treated with hydroxychloroquine. First-line conventional treatment of IPH is traditionally based on systemic corticosteroids; however, many steroid-sparing agent...
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| Veröffentlicht in: | Sarcoidosis, vasculitis, and diffuse lung diseases vasculitis, and diffuse lung diseases, 2012-03, Vol.29 (1), p.58-61 |
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| container_title | Sarcoidosis, vasculitis, and diffuse lung diseases |
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| creator | Aceti, A Sciutti, R Bracci, P R Bertelli, L Melchionda, F Cazzato, S |
| description | We report the case of a female child with Down's syndrome affected by idiopathic pulmonary haemosiderosis (IPH), who was successfully treated with hydroxychloroquine. First-line conventional treatment of IPH is traditionally based on systemic corticosteroids; however, many steroid-sparing agents are being increasingly used as adjuncts to corticosteroids in children with recurrent or refractory bleeding. The use of these drugs is particularly promising for maintenance treatment, because it tends to avoid the adverse effects of long-term corticosteroids. |
| format | Article |
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The use of these drugs is particularly promising for maintenance treatment, because it tends to avoid the adverse effects of long-term corticosteroids.</description><subject>Child, Preschool</subject><subject>Down Syndrome - complications</subject><subject>Female</subject><subject>Hemosiderosis - complications</subject><subject>Hemosiderosis - diagnosis</subject><subject>Hemosiderosis - drug therapy</subject><subject>Hemosiderosis, Pulmonary</subject><subject>Humans</subject><subject>Hydroxychloroquine - therapeutic use</subject><subject>Lung Diseases - complications</subject><subject>Lung Diseases - diagnosis</subject><subject>Lung Diseases - drug therapy</subject><subject>Predictive Value of Tests</subject><subject>Tomography, X-Ray Computed</subject><subject>Treatment Outcome</subject><issn>1124-0490</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kM1OwzAQhH0A0VJ4BeQbXCL5p05SbqhAqVSJC5yjtb1RjJI42A5V3x5LlMvujnY00nwXZMm5WBdsvWELch3jF2NlrRi7IgshJc_PckmGvXV-gtQ5Q6e5H_wI4UQ7wMFHZzHkGakbKVDTud7So0sdffbH8T7SeBpt8AM-UgMRacDJh0RhtPn8cXikvqWpQ9q7hAHSHPCGXLbQR7w97xX5fH352L4Vh_fdfvt0KCbBeSrERm4kR7RK11ArDVkazYQABWjK3MioCnlbthW3WlWttrIVVY0aDaxNKVfk4S93Cv57xpiawUWDfQ8j-jk2XFRSMV6VMlvvztZZD2ibKbghI2j-EclfS69jmw</recordid><startdate>201203</startdate><enddate>201203</enddate><creator>Aceti, A</creator><creator>Sciutti, R</creator><creator>Bracci, P R</creator><creator>Bertelli, L</creator><creator>Melchionda, F</creator><creator>Cazzato, S</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201203</creationdate><title>Idiopathic pulmonary haemosiderosis in a child with Down's syndrome: case report and review of the literature</title><author>Aceti, A ; Sciutti, R ; Bracci, P R ; Bertelli, L ; Melchionda, F ; Cazzato, S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p211t-293931eed5b8a85ba393cb022a5aec6049c57e1f6f71db57fbd3f278ebeca4c63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Child, Preschool</topic><topic>Down Syndrome - complications</topic><topic>Female</topic><topic>Hemosiderosis - complications</topic><topic>Hemosiderosis - diagnosis</topic><topic>Hemosiderosis - drug therapy</topic><topic>Hemosiderosis, Pulmonary</topic><topic>Humans</topic><topic>Hydroxychloroquine - therapeutic use</topic><topic>Lung Diseases - complications</topic><topic>Lung Diseases - diagnosis</topic><topic>Lung Diseases - drug therapy</topic><topic>Predictive Value of Tests</topic><topic>Tomography, X-Ray Computed</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Aceti, A</creatorcontrib><creatorcontrib>Sciutti, R</creatorcontrib><creatorcontrib>Bracci, P R</creatorcontrib><creatorcontrib>Bertelli, L</creatorcontrib><creatorcontrib>Melchionda, F</creatorcontrib><creatorcontrib>Cazzato, S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Sarcoidosis, vasculitis, and diffuse lung diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Aceti, A</au><au>Sciutti, R</au><au>Bracci, P R</au><au>Bertelli, L</au><au>Melchionda, F</au><au>Cazzato, S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Idiopathic pulmonary haemosiderosis in a child with Down's syndrome: case report and review of the literature</atitle><jtitle>Sarcoidosis, vasculitis, and diffuse lung diseases</jtitle><addtitle>Sarcoidosis Vasc Diffuse Lung Dis</addtitle><date>2012-03</date><risdate>2012</risdate><volume>29</volume><issue>1</issue><spage>58</spage><epage>61</epage><pages>58-61</pages><issn>1124-0490</issn><abstract>We report the case of a female child with Down's syndrome affected by idiopathic pulmonary haemosiderosis (IPH), who was successfully treated with hydroxychloroquine. 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| ispartof | Sarcoidosis, vasculitis, and diffuse lung diseases, 2012-03, Vol.29 (1), p.58-61 |
| issn | 1124-0490 |
| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Child, Preschool Down Syndrome - complications Female Hemosiderosis - complications Hemosiderosis - diagnosis Hemosiderosis - drug therapy Hemosiderosis, Pulmonary Humans Hydroxychloroquine - therapeutic use Lung Diseases - complications Lung Diseases - diagnosis Lung Diseases - drug therapy Predictive Value of Tests Tomography, X-Ray Computed Treatment Outcome |
| title | Idiopathic pulmonary haemosiderosis in a child with Down's syndrome: case report and review of the literature |
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