Pulmonary manifestations of anti-ARS antibody positive interstitial pneumonia – With or without PM/DM
Summary Background Autoantibodies against aminoacyl-tRNA synthetases (ARS) have been found to be highly specific for polymyositis and dermatomyositis (PM/DM) and to correlate strongly with complicating interstitial pneumonia (IP). The aim of the present study was to compare the clinical presentation...
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description | Summary Background Autoantibodies against aminoacyl-tRNA synthetases (ARS) have been found to be highly specific for polymyositis and dermatomyositis (PM/DM) and to correlate strongly with complicating interstitial pneumonia (IP). The aim of the present study was to compare the clinical presentations of anti-ARS antibody-positive IP patients with or without manifestations of PM/DM. Methods We retrospectively examined 36 IP patients with anti-ARS antibodies. Sixteen patients presented with and 20 without the features of PM/DM. They were divided into PM/DM-IP and idiopathic-IP (IIP) groups. Clinical symptoms, findings on physical examination, laboratory data, pulmonary function, computed tomography (CT), and bronchoalveolar lavage fluid (BALF) cell counts were compared. Results Skin findings, myalgia, and elevation of serum creatinine kinase were found in the PM/DM-IP group. Features common to both groups included: volume loss in lower bilateral lobes; ground-glass opacities, reticular shadows and traction bronchiectasis on chest CT; high percentage of lymphocytes (IIP: 44.0% ± 21.0% (mean ± SD), PM/DM-IP: 50.5% ± 23.5%) and low CD4/8 ratios (IIP: 0.36 ± 0.34, PM/DM-IP: 0.44 ± 0.42) in BALF; decreased pulmonary function, including percentage of predicted vital capacity (VC) (IIP: 80.1% ± 15.4%, PM/DM-IP: 73.6% ± 16.4%), residual volume (RV) (IIP: 70.7% ± 21.7%, PM/DM-IP: 71.5% ± 17.1%), total lung capacity (TLC) (IIP: 73.4% ± 13.6%, PM/DM-IP: 71.6% ± 13.0%), and diffusing capacity DLco (IIP: 57.5% ± 26.7%, PM/DM-IP: 46.4% ± 10.3%). Both groups achieved good responses to initial corticosteroid or immunosuppressant therapy. Conclusion Patients with anti-ARS antibody-positive IP have common pulmonary manifestations regardless of the presence of PM/DM. |
doi_str_mv | 10.1016/j.rmed.2012.09.005 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1273467379</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0954611112003460</els_id><sourcerecordid>2855135571</sourcerecordid><originalsourceid>FETCH-LOGICAL-c469t-e13cbecb85df60e790a80657602f0417b7a4bd94b55e4ffbbc390dab0d2896143</originalsourceid><addsrcrecordid>eNp9ks1qFTEUxwdR7G31BVxIQIRuZnoyySQTEKHUT2ixWMVlyGQymutMck0ylbvzHXxDn8SM95ZCF66SkN__fPzPKYonGCoMmJ2sqzCZvqoB1xWICqC5V6xwQ-qSAKP3ixWIhpYMY3xQHMa4BgBBKTwsDmqCCW9bsiq-Xs7j5J0KWzQpZwcTk0rWu4j8gJRLtjz9ePXv0vl-izY-2mSvDbIumRBTfqgRbZyZcxCr0J9fv9EXm74hH9DPfPo5ocuLk1cXj4oHgxqjebw_j4rPb15_OntXnn94-_7s9LzUlIlUGkx0Z3TXNv3AwHABqgXWcAb1ABTzjiva9YJ2TWPoMHSdJgJ61UFft4JhSo6K413cTfA_5tyNnGzUZhyVM36OEtecUMYJFxl9dgdd-zm4XF2mGIOWi4Znqt5ROvgYgxnkJtgp-yUxyGUMci2XMchlDBKEzGPIoqf70HO3_N1IbnzPwPM9oKJW4xCU0zbecoy3rKZL9hc7zmTPrq0JMmprnDa9DUYn2Xv7_zpe3pHr0TqbM343WxNv-5Uxa-TVsjDLvuAaINsE5C-wTbuO</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1266087957</pqid></control><display><type>article</type><title>Pulmonary manifestations of anti-ARS antibody positive interstitial pneumonia – With or without PM/DM</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Takato, Hazuki ; Waseda, Yuko ; Watanabe, Satoshi ; Inuzuka, Kanako ; Katayama, Nobuyuki ; Ichikawa, Yukari ; Yasui, Masahide ; Fujimura, Masaki</creator><creatorcontrib>Takato, Hazuki ; Waseda, Yuko ; Watanabe, Satoshi ; Inuzuka, Kanako ; Katayama, Nobuyuki ; Ichikawa, Yukari ; Yasui, Masahide ; Fujimura, Masaki</creatorcontrib><description>Summary Background Autoantibodies against aminoacyl-tRNA synthetases (ARS) have been found to be highly specific for polymyositis and dermatomyositis (PM/DM) and to correlate strongly with complicating interstitial pneumonia (IP). The aim of the present study was to compare the clinical presentations of anti-ARS antibody-positive IP patients with or without manifestations of PM/DM. Methods We retrospectively examined 36 IP patients with anti-ARS antibodies. Sixteen patients presented with and 20 without the features of PM/DM. They were divided into PM/DM-IP and idiopathic-IP (IIP) groups. Clinical symptoms, findings on physical examination, laboratory data, pulmonary function, computed tomography (CT), and bronchoalveolar lavage fluid (BALF) cell counts were compared. Results Skin findings, myalgia, and elevation of serum creatinine kinase were found in the PM/DM-IP group. Features common to both groups included: volume loss in lower bilateral lobes; ground-glass opacities, reticular shadows and traction bronchiectasis on chest CT; high percentage of lymphocytes (IIP: 44.0% ± 21.0% (mean ± SD), PM/DM-IP: 50.5% ± 23.5%) and low CD4/8 ratios (IIP: 0.36 ± 0.34, PM/DM-IP: 0.44 ± 0.42) in BALF; decreased pulmonary function, including percentage of predicted vital capacity (VC) (IIP: 80.1% ± 15.4%, PM/DM-IP: 73.6% ± 16.4%), residual volume (RV) (IIP: 70.7% ± 21.7%, PM/DM-IP: 71.5% ± 17.1%), total lung capacity (TLC) (IIP: 73.4% ± 13.6%, PM/DM-IP: 71.6% ± 13.0%), and diffusing capacity DLco (IIP: 57.5% ± 26.7%, PM/DM-IP: 46.4% ± 10.3%). Both groups achieved good responses to initial corticosteroid or immunosuppressant therapy. Conclusion Patients with anti-ARS antibody-positive IP have common pulmonary manifestations regardless of the presence of PM/DM.</description><identifier>ISSN: 0954-6111</identifier><identifier>EISSN: 1532-3064</identifier><identifier>DOI: 10.1016/j.rmed.2012.09.005</identifier><identifier>PMID: 23137883</identifier><language>eng</language><publisher>Kidlington: Elsevier Ltd</publisher><subject>Adolescent ; Adult ; Age ; Aged ; Amino Acyl-tRNA Synthetases - immunology ; Anti-ARS antibody ; Autoantibodies - analysis ; Biological and medical sciences ; Bronchoalveolar Lavage Fluid - cytology ; Dermatomyositis - complications ; Dermatomyositis - immunology ; Female ; Fever ; Hospitals ; Humans ; Interstital lung disease ; Lung Diseases, Interstitial - diagnostic imaging ; Lung Diseases, Interstitial - etiology ; Lung Diseases, Interstitial - immunology ; Lung Diseases, Interstitial - physiopathology ; Lung fibrosis ; Lungs ; Male ; Medical sciences ; Middle Aged ; Patients ; Personal relationships ; Physical Examination - methods ; Pneumology ; Polymyositis - complications ; Polymyositis - immunology ; Polymyositis/dermatomyositis ; Pulmonary/Respiratory ; Raynaud disease ; Respiratory system : syndromes and miscellaneous diseases ; Retrospective Studies ; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis ; Scleroderma ; Tomography, X-Ray Computed ; Total Lung Capacity ; Women ; Young Adult</subject><ispartof>Respiratory medicine, 2013-01, Vol.107 (1), p.128-133</ispartof><rights>2012</rights><rights>2014 INIST-CNRS</rights><rights>Copyright © 2012. Published by Elsevier Ltd.</rights><rights>Copyright Elsevier Limited Jan 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c469t-e13cbecb85df60e790a80657602f0417b7a4bd94b55e4ffbbc390dab0d2896143</citedby><cites>FETCH-LOGICAL-c469t-e13cbecb85df60e790a80657602f0417b7a4bd94b55e4ffbbc390dab0d2896143</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.rmed.2012.09.005$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26786247$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23137883$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Takato, Hazuki</creatorcontrib><creatorcontrib>Waseda, Yuko</creatorcontrib><creatorcontrib>Watanabe, Satoshi</creatorcontrib><creatorcontrib>Inuzuka, Kanako</creatorcontrib><creatorcontrib>Katayama, Nobuyuki</creatorcontrib><creatorcontrib>Ichikawa, Yukari</creatorcontrib><creatorcontrib>Yasui, Masahide</creatorcontrib><creatorcontrib>Fujimura, Masaki</creatorcontrib><title>Pulmonary manifestations of anti-ARS antibody positive interstitial pneumonia – With or without PM/DM</title><title>Respiratory medicine</title><addtitle>Respir Med</addtitle><description>Summary Background Autoantibodies against aminoacyl-tRNA synthetases (ARS) have been found to be highly specific for polymyositis and dermatomyositis (PM/DM) and to correlate strongly with complicating interstitial pneumonia (IP). The aim of the present study was to compare the clinical presentations of anti-ARS antibody-positive IP patients with or without manifestations of PM/DM. Methods We retrospectively examined 36 IP patients with anti-ARS antibodies. Sixteen patients presented with and 20 without the features of PM/DM. They were divided into PM/DM-IP and idiopathic-IP (IIP) groups. Clinical symptoms, findings on physical examination, laboratory data, pulmonary function, computed tomography (CT), and bronchoalveolar lavage fluid (BALF) cell counts were compared. Results Skin findings, myalgia, and elevation of serum creatinine kinase were found in the PM/DM-IP group. Features common to both groups included: volume loss in lower bilateral lobes; ground-glass opacities, reticular shadows and traction bronchiectasis on chest CT; high percentage of lymphocytes (IIP: 44.0% ± 21.0% (mean ± SD), PM/DM-IP: 50.5% ± 23.5%) and low CD4/8 ratios (IIP: 0.36 ± 0.34, PM/DM-IP: 0.44 ± 0.42) in BALF; decreased pulmonary function, including percentage of predicted vital capacity (VC) (IIP: 80.1% ± 15.4%, PM/DM-IP: 73.6% ± 16.4%), residual volume (RV) (IIP: 70.7% ± 21.7%, PM/DM-IP: 71.5% ± 17.1%), total lung capacity (TLC) (IIP: 73.4% ± 13.6%, PM/DM-IP: 71.6% ± 13.0%), and diffusing capacity DLco (IIP: 57.5% ± 26.7%, PM/DM-IP: 46.4% ± 10.3%). Both groups achieved good responses to initial corticosteroid or immunosuppressant therapy. Conclusion Patients with anti-ARS antibody-positive IP have common pulmonary manifestations regardless of the presence of PM/DM.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age</subject><subject>Aged</subject><subject>Amino Acyl-tRNA Synthetases - immunology</subject><subject>Anti-ARS antibody</subject><subject>Autoantibodies - analysis</subject><subject>Biological and medical sciences</subject><subject>Bronchoalveolar Lavage Fluid - cytology</subject><subject>Dermatomyositis - complications</subject><subject>Dermatomyositis - immunology</subject><subject>Female</subject><subject>Fever</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Interstital lung disease</subject><subject>Lung Diseases, Interstitial - diagnostic imaging</subject><subject>Lung Diseases, Interstitial - etiology</subject><subject>Lung Diseases, Interstitial - immunology</subject><subject>Lung Diseases, Interstitial - physiopathology</subject><subject>Lung fibrosis</subject><subject>Lungs</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Patients</subject><subject>Personal relationships</subject><subject>Physical Examination - methods</subject><subject>Pneumology</subject><subject>Polymyositis - complications</subject><subject>Polymyositis - immunology</subject><subject>Polymyositis/dermatomyositis</subject><subject>Pulmonary/Respiratory</subject><subject>Raynaud disease</subject><subject>Respiratory system : syndromes and miscellaneous diseases</subject><subject>Retrospective Studies</subject><subject>Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis</subject><subject>Scleroderma</subject><subject>Tomography, X-Ray Computed</subject><subject>Total Lung Capacity</subject><subject>Women</subject><subject>Young Adult</subject><issn>0954-6111</issn><issn>1532-3064</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9ks1qFTEUxwdR7G31BVxIQIRuZnoyySQTEKHUT2ixWMVlyGQymutMck0ylbvzHXxDn8SM95ZCF66SkN__fPzPKYonGCoMmJ2sqzCZvqoB1xWICqC5V6xwQ-qSAKP3ixWIhpYMY3xQHMa4BgBBKTwsDmqCCW9bsiq-Xs7j5J0KWzQpZwcTk0rWu4j8gJRLtjz9ePXv0vl-izY-2mSvDbIumRBTfqgRbZyZcxCr0J9fv9EXm74hH9DPfPo5ocuLk1cXj4oHgxqjebw_j4rPb15_OntXnn94-_7s9LzUlIlUGkx0Z3TXNv3AwHABqgXWcAb1ABTzjiva9YJ2TWPoMHSdJgJ61UFft4JhSo6K413cTfA_5tyNnGzUZhyVM36OEtecUMYJFxl9dgdd-zm4XF2mGIOWi4Znqt5ROvgYgxnkJtgp-yUxyGUMci2XMchlDBKEzGPIoqf70HO3_N1IbnzPwPM9oKJW4xCU0zbecoy3rKZL9hc7zmTPrq0JMmprnDa9DUYn2Xv7_zpe3pHr0TqbM343WxNv-5Uxa-TVsjDLvuAaINsE5C-wTbuO</recordid><startdate>20130101</startdate><enddate>20130101</enddate><creator>Takato, Hazuki</creator><creator>Waseda, Yuko</creator><creator>Watanabe, Satoshi</creator><creator>Inuzuka, Kanako</creator><creator>Katayama, Nobuyuki</creator><creator>Ichikawa, Yukari</creator><creator>Yasui, Masahide</creator><creator>Fujimura, Masaki</creator><general>Elsevier Ltd</general><general>Elsevier</general><general>Elsevier Limited</general><scope>6I.</scope><scope>AAFTH</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U9</scope><scope>ASE</scope><scope>FPQ</scope><scope>H94</scope><scope>K6X</scope><scope>K9.</scope><scope>M7N</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20130101</creationdate><title>Pulmonary manifestations of anti-ARS antibody positive interstitial pneumonia – With or without PM/DM</title><author>Takato, Hazuki ; Waseda, Yuko ; Watanabe, Satoshi ; Inuzuka, Kanako ; Katayama, Nobuyuki ; Ichikawa, Yukari ; Yasui, Masahide ; Fujimura, Masaki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c469t-e13cbecb85df60e790a80657602f0417b7a4bd94b55e4ffbbc390dab0d2896143</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age</topic><topic>Aged</topic><topic>Amino Acyl-tRNA Synthetases - immunology</topic><topic>Anti-ARS antibody</topic><topic>Autoantibodies - analysis</topic><topic>Biological and medical sciences</topic><topic>Bronchoalveolar Lavage Fluid - cytology</topic><topic>Dermatomyositis - complications</topic><topic>Dermatomyositis - immunology</topic><topic>Female</topic><topic>Fever</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Interstital lung disease</topic><topic>Lung Diseases, Interstitial - diagnostic imaging</topic><topic>Lung Diseases, Interstitial - etiology</topic><topic>Lung Diseases, Interstitial - immunology</topic><topic>Lung Diseases, Interstitial - physiopathology</topic><topic>Lung fibrosis</topic><topic>Lungs</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Patients</topic><topic>Personal relationships</topic><topic>Physical Examination - methods</topic><topic>Pneumology</topic><topic>Polymyositis - complications</topic><topic>Polymyositis - immunology</topic><topic>Polymyositis/dermatomyositis</topic><topic>Pulmonary/Respiratory</topic><topic>Raynaud disease</topic><topic>Respiratory system : syndromes and miscellaneous diseases</topic><topic>Retrospective Studies</topic><topic>Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis</topic><topic>Scleroderma</topic><topic>Tomography, X-Ray Computed</topic><topic>Total Lung Capacity</topic><topic>Women</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Takato, Hazuki</creatorcontrib><creatorcontrib>Waseda, Yuko</creatorcontrib><creatorcontrib>Watanabe, Satoshi</creatorcontrib><creatorcontrib>Inuzuka, Kanako</creatorcontrib><creatorcontrib>Katayama, Nobuyuki</creatorcontrib><creatorcontrib>Ichikawa, Yukari</creatorcontrib><creatorcontrib>Yasui, Masahide</creatorcontrib><creatorcontrib>Fujimura, Masaki</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Virology and AIDS Abstracts</collection><collection>British Nursing Index</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>British Nursing Index</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Respiratory medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Takato, Hazuki</au><au>Waseda, Yuko</au><au>Watanabe, Satoshi</au><au>Inuzuka, Kanako</au><au>Katayama, Nobuyuki</au><au>Ichikawa, Yukari</au><au>Yasui, Masahide</au><au>Fujimura, Masaki</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pulmonary manifestations of anti-ARS antibody positive interstitial pneumonia – With or without PM/DM</atitle><jtitle>Respiratory medicine</jtitle><addtitle>Respir Med</addtitle><date>2013-01-01</date><risdate>2013</risdate><volume>107</volume><issue>1</issue><spage>128</spage><epage>133</epage><pages>128-133</pages><issn>0954-6111</issn><eissn>1532-3064</eissn><abstract>Summary Background Autoantibodies against aminoacyl-tRNA synthetases (ARS) have been found to be highly specific for polymyositis and dermatomyositis (PM/DM) and to correlate strongly with complicating interstitial pneumonia (IP). The aim of the present study was to compare the clinical presentations of anti-ARS antibody-positive IP patients with or without manifestations of PM/DM. Methods We retrospectively examined 36 IP patients with anti-ARS antibodies. Sixteen patients presented with and 20 without the features of PM/DM. They were divided into PM/DM-IP and idiopathic-IP (IIP) groups. Clinical symptoms, findings on physical examination, laboratory data, pulmonary function, computed tomography (CT), and bronchoalveolar lavage fluid (BALF) cell counts were compared. Results Skin findings, myalgia, and elevation of serum creatinine kinase were found in the PM/DM-IP group. Features common to both groups included: volume loss in lower bilateral lobes; ground-glass opacities, reticular shadows and traction bronchiectasis on chest CT; high percentage of lymphocytes (IIP: 44.0% ± 21.0% (mean ± SD), PM/DM-IP: 50.5% ± 23.5%) and low CD4/8 ratios (IIP: 0.36 ± 0.34, PM/DM-IP: 0.44 ± 0.42) in BALF; decreased pulmonary function, including percentage of predicted vital capacity (VC) (IIP: 80.1% ± 15.4%, PM/DM-IP: 73.6% ± 16.4%), residual volume (RV) (IIP: 70.7% ± 21.7%, PM/DM-IP: 71.5% ± 17.1%), total lung capacity (TLC) (IIP: 73.4% ± 13.6%, PM/DM-IP: 71.6% ± 13.0%), and diffusing capacity DLco (IIP: 57.5% ± 26.7%, PM/DM-IP: 46.4% ± 10.3%). Both groups achieved good responses to initial corticosteroid or immunosuppressant therapy. Conclusion Patients with anti-ARS antibody-positive IP have common pulmonary manifestations regardless of the presence of PM/DM.</abstract><cop>Kidlington</cop><pub>Elsevier Ltd</pub><pmid>23137883</pmid><doi>10.1016/j.rmed.2012.09.005</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adolescent Adult Age Aged Amino Acyl-tRNA Synthetases - immunology Anti-ARS antibody Autoantibodies - analysis Biological and medical sciences Bronchoalveolar Lavage Fluid - cytology Dermatomyositis - complications Dermatomyositis - immunology Female Fever Hospitals Humans Interstital lung disease Lung Diseases, Interstitial - diagnostic imaging Lung Diseases, Interstitial - etiology Lung Diseases, Interstitial - immunology Lung Diseases, Interstitial - physiopathology Lung fibrosis Lungs Male Medical sciences Middle Aged Patients Personal relationships Physical Examination - methods Pneumology Polymyositis - complications Polymyositis - immunology Polymyositis/dermatomyositis Pulmonary/Respiratory Raynaud disease Respiratory system : syndromes and miscellaneous diseases Retrospective Studies Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Scleroderma Tomography, X-Ray Computed Total Lung Capacity Women Young Adult |
title | Pulmonary manifestations of anti-ARS antibody positive interstitial pneumonia – With or without PM/DM |
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