Time- and dose-dependent neuroprotective effects of sex steroid hormones on inflammatory cytokines after a traumatic brain injury

Following a traumatic brain injury (TBI), excessive release of proinflammatory cytokines is the major cause of cerebral edema and neuronal loss. This study was designed to examine changes in concentrations of some proinflammatory cytokines-including interleukin-1 beta (IL-1β), interleukin 6 (IL-6),...

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Veröffentlicht in:	Journal of neurotrauma 2013-01, Vol.30 (1), p.47-54
Hauptverfasser:	Sarkaki, Ali Reza, Khaksari Haddad, Mohammad, Soltani, Zahra, Shahrokhi, Nader, Mahmoodi, Mehdi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain damage Brain Injuries - drug therapy Brain Injuries - metabolism Cytokines Cytokines - biosynthesis Cytokines - metabolism Cytokines - physiology Disease Models, Animal Dose-Response Relationship, Drug Estrogens - administration & dosage Estrogens - therapeutic use Female Head injuries Hormones Inflammation Mediators - metabolism Inflammation Mediators - physiology Neuroprotective Agents - pharmacology Progesterone - administration & dosage Progesterone - therapeutic use Rats Rodents Time Factors
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