Faecal microbiota transplantation for severe clostridium difficile infection in the intensive care unit
We describe a case of faecal microbiota transplantation (FMT) used for severe binary toxin-positive Clostridium difficile infection in an intensive care setting. The patient was admitted to the ICU of a tertiary hospital and failed traditional maximal pharmacological management. Adjunctive therapy w...
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| Veröffentlicht in: | European journal of gastroenterology & hepatology 2013-02, Vol.25 (2), p.255-257 |
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| container_title | European journal of gastroenterology & hepatology |
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| creator | Trubiano, Jason A Gardiner, Bradley Kwong, Jason C Ward, Peter Testro, Adam G Charles, Patrick G.P |
| description | We describe a case of faecal microbiota transplantation (FMT) used for severe binary toxin-positive Clostridium difficile infection in an intensive care setting. The patient was admitted to the ICU of a tertiary hospital and failed traditional maximal pharmacological management. Adjunctive therapy with FMT given through gastroscopy resulted in resolution of the C. difficile-related symptoms. Although there is a growing experience with FMT for recurrent C. difficile infection, published evidence in severe disease is very limited. In a landscape of increasingly severe C. difficile infection, adjunctive FMT may be considered a useful early treatment option. |
| doi_str_mv | 10.1097/MEG.0b013e32835b2da9 |
| format | Article |
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| ispartof | European journal of gastroenterology & hepatology, 2013-02, Vol.25 (2), p.255-257 |
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| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Aged Clostridium difficile Combined Modality Therapy Critical Care - methods Enterocolitis, Pseudomembranous - therapy Fatal Outcome Feces - microbiology Female Gastroscopy Humans Metagenome |
| title | Faecal microbiota transplantation for severe clostridium difficile infection in the intensive care unit |
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