Unilateral Posterior Stromal Keratitis Possibly Secondary to Lyme Disease
PURPOSE:To report a case of Lyme disease presenting as unilateral posterior stromal keratitis in a pediatric patient. METHODS:Case report and review of available literature. RESULTS:A 13-year-old adolescent with unilateral painless blurry vision presented with prominent posterior corneal stromal haz...
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| Veröffentlicht in: | Cornea 2013-02, Vol.32 (2), p.196-198 |
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| container_title | Cornea |
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| creator | Oldham, Gregory W Seitzman, Gerami D |
| description | PURPOSE:To report a case of Lyme disease presenting as unilateral posterior stromal keratitis in a pediatric patient.
METHODS:Case report and review of available literature.
RESULTS:A 13-year-old adolescent with unilateral painless blurry vision presented with prominent posterior corneal stromal haze. A positive Borrelia burgdorferi antibody enzyme immunoassay and Western blot analysis (9 of 10 reactive immunoglobulin G bands and 1 of 3 immunoglobulin M bands) confirmed the diagnosis. Treatment with oral antibiotics and topical corticosteroids were necessary for resolution.
CONCLUSIONS:Lyme disease may present as a unilateral posterior stromal keratitis, even in a pediatric population. Treatment requires both systemic and topical therapy. |
| doi_str_mv | 10.1097/ICO.0b013e318274d85d |
| format | Article |
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METHODS:Case report and review of available literature.
RESULTS:A 13-year-old adolescent with unilateral painless blurry vision presented with prominent posterior corneal stromal haze. A positive Borrelia burgdorferi antibody enzyme immunoassay and Western blot analysis (9 of 10 reactive immunoglobulin G bands and 1 of 3 immunoglobulin M bands) confirmed the diagnosis. Treatment with oral antibiotics and topical corticosteroids were necessary for resolution.
CONCLUSIONS:Lyme disease may present as a unilateral posterior stromal keratitis, even in a pediatric population. Treatment requires both systemic and topical therapy.</description><identifier>ISSN: 0277-3740</identifier><identifier>EISSN: 1536-4798</identifier><identifier>DOI: 10.1097/ICO.0b013e318274d85d</identifier><identifier>PMID: 23132459</identifier><language>eng</language><publisher>United States: Lippincott Williams & Wilkins, Inc</publisher><subject>Adolescent ; Anti-Bacterial Agents - therapeutic use ; Antibodies, Bacterial - blood ; Blotting, Western ; Borrelia burgdorferi - immunology ; Corneal Stroma - pathology ; Doxycycline - therapeutic use ; Drug Therapy, Combination ; Female ; Glucocorticoids - therapeutic use ; Humans ; Immunoenzyme Techniques ; Immunoglobulin G - immunology ; Immunoglobulin M - immunology ; Keratitis - diagnosis ; Keratitis - drug therapy ; Keratitis - etiology ; Lyme Disease - complications ; Lyme Disease - drug therapy ; Lyme Disease - immunology ; Prednisolone - analogs & derivatives ; Prednisolone - therapeutic use</subject><ispartof>Cornea, 2013-02, Vol.32 (2), p.196-198</ispartof><rights>2013 Lippincott Williams & Wilkins, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c356d-776f60f3fcbd0b5072e7885721d80535ee6e63246298fee456d95760ceffaa4f3</citedby><cites>FETCH-LOGICAL-c356d-776f60f3fcbd0b5072e7885721d80535ee6e63246298fee456d95760ceffaa4f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23132459$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Oldham, Gregory W</creatorcontrib><creatorcontrib>Seitzman, Gerami D</creatorcontrib><title>Unilateral Posterior Stromal Keratitis Possibly Secondary to Lyme Disease</title><title>Cornea</title><addtitle>Cornea</addtitle><description>PURPOSE:To report a case of Lyme disease presenting as unilateral posterior stromal keratitis in a pediatric patient.
METHODS:Case report and review of available literature.
RESULTS:A 13-year-old adolescent with unilateral painless blurry vision presented with prominent posterior corneal stromal haze. A positive Borrelia burgdorferi antibody enzyme immunoassay and Western blot analysis (9 of 10 reactive immunoglobulin G bands and 1 of 3 immunoglobulin M bands) confirmed the diagnosis. Treatment with oral antibiotics and topical corticosteroids were necessary for resolution.
CONCLUSIONS:Lyme disease may present as a unilateral posterior stromal keratitis, even in a pediatric population. Treatment requires both systemic and topical therapy.</description><subject>Adolescent</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Antibodies, Bacterial - blood</subject><subject>Blotting, Western</subject><subject>Borrelia burgdorferi - immunology</subject><subject>Corneal Stroma - pathology</subject><subject>Doxycycline - therapeutic use</subject><subject>Drug Therapy, Combination</subject><subject>Female</subject><subject>Glucocorticoids - therapeutic use</subject><subject>Humans</subject><subject>Immunoenzyme Techniques</subject><subject>Immunoglobulin G - immunology</subject><subject>Immunoglobulin M - immunology</subject><subject>Keratitis - diagnosis</subject><subject>Keratitis - drug therapy</subject><subject>Keratitis - etiology</subject><subject>Lyme Disease - complications</subject><subject>Lyme Disease - drug therapy</subject><subject>Lyme Disease - immunology</subject><subject>Prednisolone - analogs & derivatives</subject><subject>Prednisolone - therapeutic use</subject><issn>0277-3740</issn><issn>1536-4798</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtOwzAQRS0EoqXwBwhlySbFbydLVF4VlYpUuo6cZKwGnLrYiar-Pa5aWLBgNaOZe2euDkLXBI8JztXddDIf4xITBoxkVPE6E_UJGhLBZMpVnp2iIaZKpUxxPEAXIXxgjJWS9BwNKCOMcpEP0XS5bqzuwGubvLkQm8b5ZNF518bJa5x3TdeE_S40pd0lC6jcutZ-l3Qume1aSB6aADrAJToz2ga4OtYRWj49vk9e0tn8eTq5n6UVE7JOYwIjsWGmKmtcCqwoqCwTipI6w4IJAAkyhpM0zwwAj55cKIkrMEZrbtgI3R7ubrz76iF0RduECqzVa3B9KAhVjAlCOItSfpBWPsb3YIqNb9qYvSC42EMsIsTiL8Rouzl-6MsW6l_TD7UoyA6CrbORWPi0_RZ8sQJtu9X_t78B7riARA</recordid><startdate>201302</startdate><enddate>201302</enddate><creator>Oldham, Gregory W</creator><creator>Seitzman, Gerami D</creator><general>Lippincott Williams & Wilkins, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201302</creationdate><title>Unilateral Posterior Stromal Keratitis Possibly Secondary to Lyme Disease</title><author>Oldham, Gregory W ; Seitzman, Gerami D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c356d-776f60f3fcbd0b5072e7885721d80535ee6e63246298fee456d95760ceffaa4f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adolescent</topic><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>Antibodies, Bacterial - blood</topic><topic>Blotting, Western</topic><topic>Borrelia burgdorferi - immunology</topic><topic>Corneal Stroma - pathology</topic><topic>Doxycycline - therapeutic use</topic><topic>Drug Therapy, Combination</topic><topic>Female</topic><topic>Glucocorticoids - therapeutic use</topic><topic>Humans</topic><topic>Immunoenzyme Techniques</topic><topic>Immunoglobulin G - immunology</topic><topic>Immunoglobulin M - immunology</topic><topic>Keratitis - diagnosis</topic><topic>Keratitis - drug therapy</topic><topic>Keratitis - etiology</topic><topic>Lyme Disease - complications</topic><topic>Lyme Disease - drug therapy</topic><topic>Lyme Disease - immunology</topic><topic>Prednisolone - analogs & derivatives</topic><topic>Prednisolone - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Oldham, Gregory W</creatorcontrib><creatorcontrib>Seitzman, Gerami D</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cornea</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Oldham, Gregory W</au><au>Seitzman, Gerami D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Unilateral Posterior Stromal Keratitis Possibly Secondary to Lyme Disease</atitle><jtitle>Cornea</jtitle><addtitle>Cornea</addtitle><date>2013-02</date><risdate>2013</risdate><volume>32</volume><issue>2</issue><spage>196</spage><epage>198</epage><pages>196-198</pages><issn>0277-3740</issn><eissn>1536-4798</eissn><abstract>PURPOSE:To report a case of Lyme disease presenting as unilateral posterior stromal keratitis in a pediatric patient.
METHODS:Case report and review of available literature.
RESULTS:A 13-year-old adolescent with unilateral painless blurry vision presented with prominent posterior corneal stromal haze. A positive Borrelia burgdorferi antibody enzyme immunoassay and Western blot analysis (9 of 10 reactive immunoglobulin G bands and 1 of 3 immunoglobulin M bands) confirmed the diagnosis. Treatment with oral antibiotics and topical corticosteroids were necessary for resolution.
CONCLUSIONS:Lyme disease may present as a unilateral posterior stromal keratitis, even in a pediatric population. Treatment requires both systemic and topical therapy.</abstract><cop>United States</cop><pub>Lippincott Williams & Wilkins, Inc</pub><pmid>23132459</pmid><doi>10.1097/ICO.0b013e318274d85d</doi><tpages>3</tpages></addata></record> |
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| ispartof | Cornea, 2013-02, Vol.32 (2), p.196-198 |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adolescent Anti-Bacterial Agents - therapeutic use Antibodies, Bacterial - blood Blotting, Western Borrelia burgdorferi - immunology Corneal Stroma - pathology Doxycycline - therapeutic use Drug Therapy, Combination Female Glucocorticoids - therapeutic use Humans Immunoenzyme Techniques Immunoglobulin G - immunology Immunoglobulin M - immunology Keratitis - diagnosis Keratitis - drug therapy Keratitis - etiology Lyme Disease - complications Lyme Disease - drug therapy Lyme Disease - immunology Prednisolone - analogs & derivatives Prednisolone - therapeutic use |
| title | Unilateral Posterior Stromal Keratitis Possibly Secondary to Lyme Disease |
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