Abnormal expression of PI3K isoforms in patients with tobacco-related oral squamous cell carcinoma

The phosphatidylinositol 3-kinase (PI3K) signaling regulates several cellular functions such as motility, proliferation, angiogenesis and survival. Since there is no information on expression of PI3K isoforms in oral cancer, we studied the expression of different isoforms of PI3K (p110α, p110γ, PI3K...

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Veröffentlicht in:	Clinica chimica acta 2013-02, Vol.416, p.100-106
Hauptverfasser:	Garg, Richa, Kapoor, Vaishali, Mittal, Manasi, Singh, Manoj K., Shukla, Nootan K., Das, Satya N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - physiopathology Enzyme-Linked Immunosorbent Assay Expression Female Gene Expression Regulation, Neoplastic Humans IHC Immunohistochemistry Isoforms Male Middle Aged Mouth Neoplasms - genetics Mouth Neoplasms - physiopathology Nicotiana Oral cancer Phosphatidylinositol 3-Kinase - blood Phosphatidylinositol 3-Kinase - genetics Phosphatidylinositol 3-Kinase - metabolism PI3K Polymerase Chain Reaction Protein Isoforms RNA, Messenger - metabolism SPR Transcriptome
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