The role of mass spectrometry in the analysis of vitamin D compounds
This review highlights the superseding role of mass spectrometry in the structural characterization and quantitation of vitamin D compounds in comparison to other analytical methods (e.g., UV, bioassays) that lack the sensitivity and specificity of mass spectrometry. After a short introduction to th...
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| Veröffentlicht in: | Mass spectrometry reviews 2013-01, Vol.32 (1), p.72-86 |
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| container_title | Mass spectrometry reviews |
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| creator | Gathungu, Rose M. Flarakos, Caroline C. Satyanarayana Reddy, G. Vouros, Paul |
| description | This review highlights the superseding role of mass spectrometry in the structural characterization and quantitation of vitamin D compounds in comparison to other analytical methods (e.g., UV, bioassays) that lack the sensitivity and specificity of mass spectrometry. After a short introduction to the biochemistry of vitamin D compounds, an overview of the current techniques to characterize and quantitate vitamin D compounds is given with emphasis on the contribution of mass spectrometry. © 2012 Wiley Periodicals, Inc., Mass Spec Rev 32:72–86, 2013 |
| doi_str_mv | 10.1002/mas.21353 |
| format | Article |
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| fulltext | fulltext |
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| ispartof | Mass spectrometry reviews, 2013-01, Vol.32 (1), p.72-86 |
| issn | 0277-7037 1098-2787 |
| language | eng |
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| source | Wiley Online Library - AutoHoldings Journals; MEDLINE |
| subjects | 1α,25 dihydroxy‐3‐epi vitamin D3 1α,25‐dihydroxyvitamin D3 25 dihydroxy-3-epi vitamin D3 25-dihydroxyvitamin D3 Animals Chromatography, Liquid - methods Chromatography, Liquid - statistics & numerical data GC-MS Humans LC-MS/MS Mass Spectrometry - methods Vitamin D - analogs & derivatives Vitamin D - chemistry Vitamin D - metabolism vitamin D analogs |
| title | The role of mass spectrometry in the analysis of vitamin D compounds |
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