Interconversion of ephedrine and pseudoephedrine during chemical derivatization

Gas chromatography–mass spectrometry (GC‐MS) analysis after heptafluorobutyric anhydride (HFBA) derivatization was one of the published methods used for the quantification of ephedrine (EP) and pseudoephedrine (PE) in urine. This method allows the clear separation of the derivatized diastereoisomers...

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Veröffentlicht in:	Drug testing and analysis 2012-12, Vol.4 (12), p.1028-1033
Hauptverfasser:	Wong, Colton H. F., Ho, Emmie N. M., Kwok, W. H., Leung, David K. K., Leung, Gary N. W., Tang, Francis P. W., Wong, April S. Y., Wong, Jenny K. Y., Yu, Nola H., Wan, Terence S. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetic Anhydrides - chemistry Acylation Chromatography, High Pressure Liquid ephedrine Ephedrine - chemistry Ephedrine - urine Fluoroacetates - chemistry Fluorocarbons - chemistry gas chromatography Gas Chromatography-Mass Spectrometry Humans interconversion Isomerism mass spectrometry Models, Chemical Performance-Enhancing Substances - chemistry Performance-Enhancing Substances - urine pseudoephedrine Pseudoephedrine - chemistry Pseudoephedrine - urine Reproducibility of Results Substance Abuse Detection - methods Tandem Mass Spectrometry ultra-high performance liquid chromatography
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