Overview of DNA microarrays: types, applications, and their future
This unit provides an overview of DNA microarrays. Microarrays are a technology in which thousands of nucleic acids are bound to a surface and are used to measure the relative concentration of nucleic acid sequences in a mixture via hybridization and subsequent detection of the hybridization events....
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| Veröffentlicht in: | Current protocols in molecular biology (Print) 2013-01, Vol.Chapter 22 (1), p.Unit 22.1.-Unit 22.1. |
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| container_end_page | Unit 22.1. |
|---|---|
| container_issue | 1 |
| container_start_page | Unit 22.1. |
| container_title | Current protocols in molecular biology (Print) |
| container_volume | Chapter 22 |
| creator | Bumgarner, Roger |
| description | This unit provides an overview of DNA microarrays. Microarrays are a technology in which thousands of nucleic acids are bound to a surface and are used to measure the relative concentration of nucleic acid sequences in a mixture via hybridization and subsequent detection of the hybridization events. This overview first discusses the history of microarrays and the antecedent technologies that led to their development. This is followed by discussion of the methods of manufacture of microarrays and the most common biological applications. The unit ends with a brief description of the limitations of microarrays and discusses how microarrays are being rapidly replaced by DNA sequencing technologies. |
| doi_str_mv | 10.1002/0471142727.mb2201s101 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1934-3639 |
| ispartof | Current protocols in molecular biology (Print), 2013-01, Vol.Chapter 22 (1), p.Unit 22.1.-Unit 22.1. |
| issn | 1934-3639 1934-3647 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1273211333 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Gene Expression Profiling - history Gene Expression Profiling - methods History, 20th Century History, 21st Century Molecular Biology - history Molecular Biology - methods Oligonucleotide Array Sequence Analysis - history Oligonucleotide Array Sequence Analysis - methods |
| title | Overview of DNA microarrays: types, applications, and their future |
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