Lithium Treatment Moderate-Dose Use Study (LiTMUS) for Bipolar Disorder: A Randomized Comparative Effectiveness Trial of Optimized Personalized Treatment With and Without Lithium

Personalized treatment of bipolar I or II disorder that includes lithium does not appear to be superior to individualized care using other evidence-based treatments. In a 6-month comparison study, the overall remission rate was 27%, with no difference in remission or adverse events between the lithi...

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Veröffentlicht in:	The American journal of psychiatry 2013-01, Vol.170 (1), p.102-110
Hauptverfasser:	Nierenberg, Andrew A., Friedman, Edward S., Bowden, Charles L., Sylvia, Louisa G., Thase, Michael E., Ketter, Terence, Ostacher, Michael J., Leon, Andrew C., Reilly-Harrington, Noreen, Iosifescu, Dan V., Pencina, Michael, Severe, Joanne B., Calabrese, Joseph R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adult and adolescent clinical studies Affect - drug effects Antimanic Agents - administration & dosage Antimanic Agents - adverse effects Antipsychotic Agents - administration & dosage Antipsychotic Agents - adverse effects Biological and medical sciences Bipolar disorder Bipolar Disorder - diagnosis Bipolar Disorder - drug therapy Bipolar Disorder - psychology Bipolar disorders Clinical outcomes Clinical trials Combined Modality Therapy Disability Evaluation Dose-Response Relationship, Drug Drug dosages Female Follow-Up Studies Humans Lithium Lithium Carbonate - administration & dosage Lithium Carbonate - adverse effects Male Medical sciences Middle Aged Mood disorders Neuropharmacology Pharmacology. Drug treatments Precision Medicine Psychiatric Status Rating Scales Psychiatry Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychopharmacology Psychotropic drugs
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