Non-natural Elemane as the “Stepping Stone” for the Synthesis of Germacrane and Guaiane Sesquiterpenes

The synthesis of hydroxyelemane 5 from (R)-carvone and its utilization as a common synthetic scaffold to produce structurally diverse germacrane and guaiane sesquiterpenes are described. A highly enantio- and stereoselective biomimetic tandem oxy-Cope/ene rearrangement was used as the key reaction t...

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Veröffentlicht in:	Organic letters 2013-01, Vol.15 (1), p.152-155
Hauptverfasser:	Anagnostaki, Elissavet E, Zografos, Alexandros L
Format:	Artikel
Sprache:	eng
Schlagworte:	Cyclization Molecular Structure Monoterpenes - chemistry Sesquiterpenes, Guaiane - chemical synthesis Sesquiterpenes, Guaiane - chemistry Stereoisomerism
Online-Zugang:	Volltext
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