Expression of TLR3, 4, 7 and 9 in cutaneous malignant melanoma: relationship with clinicopathological characteristics and prognosis

Toll-like receptors (TLRs) have achieved an extraordinary amount of interest in cancer research due to their role in tumor progression. The aim of this study was to investigate the expression and clinical relevance of TLR3, 4, 7 and 9 in cutaneous malignant melanoma (CMM). The expression levels of T...

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Veröffentlicht in:	Archives of Dermatological Research 2013, Vol.305 (1), p.59-67
Hauptverfasser:	Eiró, N., Ovies, C., Fernandez-Garcia, B., Álvarez-Cuesta, C. C., González, L., González, L. O., Vizoso, F. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biomarkers, Tumor - analysis Chi-Square Distribution Dermatology Disease-Free Survival Female Humans Immunohistochemistry Inflammation Kaplan-Meier Estimate Male Medical prognosis Medicine Medicine & Public Health Melanoma Melanoma - immunology Melanoma - mortality Melanoma - pathology Melanoma - therapy Middle Aged Original Paper Skin cancer Skin Neoplasms - immunology Skin Neoplasms - mortality Skin Neoplasms - pathology Skin Neoplasms - therapy Time Factors TLR3 protein TLR4 protein TLR9 protein Toll-Like Receptor 3 - analysis Toll-Like Receptor 4 - analysis Toll-Like Receptor 7 - analysis Toll-Like Receptor 8 - analysis Toll-like receptors Treatment Outcome Tumor cells Tumors Up-Regulation Young Adult
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