Contemporary Outcomes After Endovascular Treatment for Aorto-Iliac Artery Disease

Background: The patency and complications in aorto-iliac (AI) stenting remain poorly understood. The aim of this paper was to investigate the safety and efficacy after AI stenting. Methods and Results: This study was performed as a large-scale multicenter, retrospective registry. A total of 2,147 co...

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Veröffentlicht in:Circulation Journal 2012, Vol.76(11), pp.2697-2704
Hauptverfasser: Soga, Yoshimitsu, Iida, Osamu, Kawasaki, Daizo, Yamauchi, Yasutaka, Suzuki, Kenji, Hirano, Keisuke, Koshida, Ryoji, Kamoi, Daisuke, Tazaki, Junichi, Higashitani, Michiaki, Shintani, Yoshiaki, Yamaoka, Terutoshi, Okazaki, Shinya, Suematsu, Nobuhiro, Tsuchiya, Taketsugu, Miyashita, Yusuke, Shinozaki, Norihiko, Takahashi, Hiroki, on behalf of REAL-AI investigators
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container_end_page 2704
container_issue 11
container_start_page 2697
container_title Circulation Journal
container_volume 76
creator Soga, Yoshimitsu
Iida, Osamu
Kawasaki, Daizo
Yamauchi, Yasutaka
Suzuki, Kenji
Hirano, Keisuke
Koshida, Ryoji
Kamoi, Daisuke
Tazaki, Junichi
Higashitani, Michiaki
Shintani, Yoshiaki
Yamaoka, Terutoshi
Okazaki, Shinya
Suematsu, Nobuhiro
Tsuchiya, Taketsugu
Miyashita, Yusuke
Shinozaki, Norihiko
Takahashi, Hiroki
on behalf of REAL-AI investigators
description Background: The patency and complications in aorto-iliac (AI) stenting remain poorly understood. The aim of this paper was to investigate the safety and efficacy after AI stenting. Methods and Results: This study was performed as a large-scale multicenter, retrospective registry. A total of 2,147 consecutive patients with AI disease were enrolled. The safety endpoints were procedure success, complications and 30-day mortality. The efficacy endpoints were primary, assisted primary and secondary patency, overall survival, freedom from major adverse cardiovascular events (MACE; all-cause death, myocardial infarction and stroke), and major adverse cardiovascular and limb events (MACLE; any repeat revascularization for limb and leg amputation in addition to MACE). Procedure success, complication rate and 30-day mortality were 97.6%, 6.4% and 0.7%. Primary patency was 92.5%, 82.6% and 77.5% at 1, 3 and 5 years, assisted primary patency was 97.0%, 92.7% and 91.9% at 1, 3 and 5 years and secondary patency was 99.0%, 98.7% and 98.5% at 1, 3 and 5 years. The overall survival rate was 95.0%, 87.6%, and 79.3% at 1, 3 and 5 years. The cause of death was cardiovascular in 44.1%. Freedom from MACE (MACLE) was 93.3% (89.9%), 84.4% (76.7%), and 74.9% (66.8%) at 1, 3 and 5 years. Female gender, diabetes, renal failure, absence of aspirin, reference vessel diameter
doi_str_mv 10.1253/circj.CJ-12-0492
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The aim of this paper was to investigate the safety and efficacy after AI stenting. Methods and Results: This study was performed as a large-scale multicenter, retrospective registry. A total of 2,147 consecutive patients with AI disease were enrolled. The safety endpoints were procedure success, complications and 30-day mortality. The efficacy endpoints were primary, assisted primary and secondary patency, overall survival, freedom from major adverse cardiovascular events (MACE; all-cause death, myocardial infarction and stroke), and major adverse cardiovascular and limb events (MACLE; any repeat revascularization for limb and leg amputation in addition to MACE). Procedure success, complication rate and 30-day mortality were 97.6%, 6.4% and 0.7%. Primary patency was 92.5%, 82.6% and 77.5% at 1, 3 and 5 years, assisted primary patency was 97.0%, 92.7% and 91.9% at 1, 3 and 5 years and secondary patency was 99.0%, 98.7% and 98.5% at 1, 3 and 5 years. The overall survival rate was 95.0%, 87.6%, and 79.3% at 1, 3 and 5 years. The cause of death was cardiovascular in 44.1%. Freedom from MACE (MACLE) was 93.3% (89.9%), 84.4% (76.7%), and 74.9% (66.8%) at 1, 3 and 5 years. Female gender, diabetes, renal failure, absence of aspirin, reference vessel diameter &lt;8.0mm and outflow lesion were found to be independent predictors of primary patency. Conclusions: The safety and efficacy after AI stenting are feasible compared to surgical reconstruction.  (Circ J 2012; 76: 2697–2704)</description><identifier>ISSN: 1346-9843</identifier><identifier>EISSN: 1347-4820</identifier><identifier>DOI: 10.1253/circj.CJ-12-0492</identifier><identifier>PMID: 22864278</identifier><language>eng</language><publisher>Japan: The Japanese Circulation Society</publisher><subject>Aged ; Aortic Diseases - mortality ; Aortic Diseases - physiopathology ; Aortic Diseases - surgery ; Aorto-iliac disease ; Blood Vessel Prosthesis Implantation ; Disease-Free Survival ; Endovascular Procedures ; Endovascular therapy ; Female ; Humans ; Iliac Artery ; Male ; Middle Aged ; Patency ; Registries ; Retrospective Studies ; Sex Factors ; Stents ; Survival Rate ; Time Factors ; Vascular Patency</subject><ispartof>Circulation Journal, 2012, Vol.76(11), pp.2697-2704</ispartof><rights>2012 THE JAPANESE CIRCULATION SOCIETY</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c643t-a513ee0bc2f62363b7a72215aa61438cd47a1ec82d07881bd19719520a44e0c53</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1877,4010,27900,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22864278$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Soga, Yoshimitsu</creatorcontrib><creatorcontrib>Iida, Osamu</creatorcontrib><creatorcontrib>Kawasaki, Daizo</creatorcontrib><creatorcontrib>Yamauchi, Yasutaka</creatorcontrib><creatorcontrib>Suzuki, Kenji</creatorcontrib><creatorcontrib>Hirano, Keisuke</creatorcontrib><creatorcontrib>Koshida, Ryoji</creatorcontrib><creatorcontrib>Kamoi, Daisuke</creatorcontrib><creatorcontrib>Tazaki, Junichi</creatorcontrib><creatorcontrib>Higashitani, Michiaki</creatorcontrib><creatorcontrib>Shintani, Yoshiaki</creatorcontrib><creatorcontrib>Yamaoka, Terutoshi</creatorcontrib><creatorcontrib>Okazaki, Shinya</creatorcontrib><creatorcontrib>Suematsu, Nobuhiro</creatorcontrib><creatorcontrib>Tsuchiya, Taketsugu</creatorcontrib><creatorcontrib>Miyashita, Yusuke</creatorcontrib><creatorcontrib>Shinozaki, Norihiko</creatorcontrib><creatorcontrib>Takahashi, Hiroki</creatorcontrib><creatorcontrib>on behalf of REAL-AI investigators</creatorcontrib><creatorcontrib>REAL-AI investigators</creatorcontrib><title>Contemporary Outcomes After Endovascular Treatment for Aorto-Iliac Artery Disease</title><title>Circulation Journal</title><addtitle>Circ J</addtitle><description>Background: The patency and complications in aorto-iliac (AI) stenting remain poorly understood. The aim of this paper was to investigate the safety and efficacy after AI stenting. Methods and Results: This study was performed as a large-scale multicenter, retrospective registry. A total of 2,147 consecutive patients with AI disease were enrolled. The safety endpoints were procedure success, complications and 30-day mortality. The efficacy endpoints were primary, assisted primary and secondary patency, overall survival, freedom from major adverse cardiovascular events (MACE; all-cause death, myocardial infarction and stroke), and major adverse cardiovascular and limb events (MACLE; any repeat revascularization for limb and leg amputation in addition to MACE). Procedure success, complication rate and 30-day mortality were 97.6%, 6.4% and 0.7%. Primary patency was 92.5%, 82.6% and 77.5% at 1, 3 and 5 years, assisted primary patency was 97.0%, 92.7% and 91.9% at 1, 3 and 5 years and secondary patency was 99.0%, 98.7% and 98.5% at 1, 3 and 5 years. The overall survival rate was 95.0%, 87.6%, and 79.3% at 1, 3 and 5 years. The cause of death was cardiovascular in 44.1%. Freedom from MACE (MACLE) was 93.3% (89.9%), 84.4% (76.7%), and 74.9% (66.8%) at 1, 3 and 5 years. Female gender, diabetes, renal failure, absence of aspirin, reference vessel diameter &lt;8.0mm and outflow lesion were found to be independent predictors of primary patency. Conclusions: The safety and efficacy after AI stenting are feasible compared to surgical reconstruction.  (Circ J 2012; 76: 2697–2704)</description><subject>Aged</subject><subject>Aortic Diseases - mortality</subject><subject>Aortic Diseases - physiopathology</subject><subject>Aortic Diseases - surgery</subject><subject>Aorto-iliac disease</subject><subject>Blood Vessel Prosthesis Implantation</subject><subject>Disease-Free Survival</subject><subject>Endovascular Procedures</subject><subject>Endovascular therapy</subject><subject>Female</subject><subject>Humans</subject><subject>Iliac Artery</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Patency</subject><subject>Registries</subject><subject>Retrospective Studies</subject><subject>Sex Factors</subject><subject>Stents</subject><subject>Survival Rate</subject><subject>Time Factors</subject><subject>Vascular Patency</subject><issn>1346-9843</issn><issn>1347-4820</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkMtLw0AQhxdRtD7uniRHL9F9Jbs5llirIoig52W6mWhKkq27G6H_vamt9jIP-OYH8xFyyegN45m4tY23y5vyKWU8pbLgB2TChFSp1Jwe_s55WmgpTshpCEtKeUGz4piccK5zyZWekNfS9RG7lfPg18nLEK3rMCTTOqJPZn3lviHYoQWfvHmE2GEfk9r5ZOp8dOlj24BNpn6E18ldExACnpOjGtqAF7t-Rt7vZ2_lQ_r8Mn8sp8-pzaWIKWRMINKF5XXORS4WChTnLAPImRTaVlIBQ6t5RZXWbFGxQrEi4xSkRGozcUaut7kr774GDNF0TbDYttCjG4JhXAmWZVrREaVb1HoXgsfarHzTjQ8bRs1GpPkVacqncTMbkePJ1S59WHRY_R_8mRuB-RZYhggf-A-Aj41tcZeocsPYpu6j98QneIO9-AFL9YjZ</recordid><startdate>2012</startdate><enddate>2012</enddate><creator>Soga, Yoshimitsu</creator><creator>Iida, Osamu</creator><creator>Kawasaki, Daizo</creator><creator>Yamauchi, Yasutaka</creator><creator>Suzuki, Kenji</creator><creator>Hirano, Keisuke</creator><creator>Koshida, Ryoji</creator><creator>Kamoi, Daisuke</creator><creator>Tazaki, Junichi</creator><creator>Higashitani, Michiaki</creator><creator>Shintani, Yoshiaki</creator><creator>Yamaoka, Terutoshi</creator><creator>Okazaki, Shinya</creator><creator>Suematsu, Nobuhiro</creator><creator>Tsuchiya, Taketsugu</creator><creator>Miyashita, Yusuke</creator><creator>Shinozaki, Norihiko</creator><creator>Takahashi, Hiroki</creator><creator>on behalf of REAL-AI investigators</creator><general>The Japanese Circulation Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2012</creationdate><title>Contemporary Outcomes After Endovascular Treatment for Aorto-Iliac Artery Disease</title><author>Soga, Yoshimitsu ; 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The aim of this paper was to investigate the safety and efficacy after AI stenting. Methods and Results: This study was performed as a large-scale multicenter, retrospective registry. A total of 2,147 consecutive patients with AI disease were enrolled. The safety endpoints were procedure success, complications and 30-day mortality. The efficacy endpoints were primary, assisted primary and secondary patency, overall survival, freedom from major adverse cardiovascular events (MACE; all-cause death, myocardial infarction and stroke), and major adverse cardiovascular and limb events (MACLE; any repeat revascularization for limb and leg amputation in addition to MACE). Procedure success, complication rate and 30-day mortality were 97.6%, 6.4% and 0.7%. Primary patency was 92.5%, 82.6% and 77.5% at 1, 3 and 5 years, assisted primary patency was 97.0%, 92.7% and 91.9% at 1, 3 and 5 years and secondary patency was 99.0%, 98.7% and 98.5% at 1, 3 and 5 years. The overall survival rate was 95.0%, 87.6%, and 79.3% at 1, 3 and 5 years. The cause of death was cardiovascular in 44.1%. Freedom from MACE (MACLE) was 93.3% (89.9%), 84.4% (76.7%), and 74.9% (66.8%) at 1, 3 and 5 years. Female gender, diabetes, renal failure, absence of aspirin, reference vessel diameter &lt;8.0mm and outflow lesion were found to be independent predictors of primary patency. Conclusions: The safety and efficacy after AI stenting are feasible compared to surgical reconstruction.  (Circ J 2012; 76: 2697–2704)</abstract><cop>Japan</cop><pub>The Japanese Circulation Society</pub><pmid>22864278</pmid><doi>10.1253/circj.CJ-12-0492</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record>
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subjects Aged
Aortic Diseases - mortality
Aortic Diseases - physiopathology
Aortic Diseases - surgery
Aorto-iliac disease
Blood Vessel Prosthesis Implantation
Disease-Free Survival
Endovascular Procedures
Endovascular therapy
Female
Humans
Iliac Artery
Male
Middle Aged
Patency
Registries
Retrospective Studies
Sex Factors
Stents
Survival Rate
Time Factors
Vascular Patency
title Contemporary Outcomes After Endovascular Treatment for Aorto-Iliac Artery Disease
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