Testosterone treatment improves metabolic syndrome-induced adipose tissue derangements

We recently demonstrated that testosterone dosing ameliorated the metabolic profile and reduced visceral adipose tissue (VAT) in a high-fat diet (HFD)-induced rabbit model of metabolic syndrome (MetS). We studied the effects of HFD and in vivo testosterone dosing on VAT function and the adipogenic c...

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Veröffentlicht in:	Journal of endocrinology 2012-12, Vol.215 (3), p.347-362
Hauptverfasser:	Maneschi, Elena, Morelli, Annamaria, Filippi, Sandra, Cellai, Ilaria, Comeglio, Paolo, Mazzanti, Benedetta, Mello, Tommaso, Calcagno, Alessandra, Sarchielli, Erica, Vignozzi, Linda, Saad, Farid, Vettor, Roberto, Vannelli, Gabriella B, Maggi, Mario
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes - cytology Adipocytes - drug effects Adipose Tissue - drug effects Adipose Tissue - metabolism Adipose Tissue - pathology Animals Biological and medical sciences Cell Differentiation - drug effects Cell Differentiation - genetics Cells, Cultured Flow Cytometry Fundamental and applied biological sciences. Psychology Immunohistochemistry Intra-Abdominal Fat - drug effects Intra-Abdominal Fat - metabolism Intra-Abdominal Fat - pathology Male Medical sciences Metabolic diseases Metabolic Syndrome - drug therapy Metabolic Syndrome - pathology Miscellaneous Other metabolic disorders Rabbits Receptors, Androgen - metabolism Regular papers Testosterone - therapeutic use Vertebrates: endocrinology
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