Broadly neutralizing antibodies against HIV-1: Templates for a vaccine

Abstract The need for an effective vaccine to prevent the global spread of human immunodeficiency virus type 1 (HIV-1) is well recognized. Passive immunization and challenge studies in non-human primates testify that broadly neutralizing antibodies (BrNAbs) can accomplish protection against infectio...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 2013-01, Vol.435 (1), p.46-56
Hauptverfasser:	van Gils, Marit J, Sanders, Rogier W
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS Vaccines - administration & dosage AIDS Vaccines - immunology Animals Antibodies Antibodies, Neutralizing Antigens, Viral - chemistry Antigens, Viral - immunology Broadly neutralizing antibodies env Gene Products, Human Immunodeficiency Virus - chemistry env Gene Products, Human Immunodeficiency Virus - immunology Envelope glycoprotein Envelopes Epitopes Glycoproteins HIV Antibodies - administration & dosage HIV Antibodies - chemistry HIV Antibodies - immunology HIV Infections - immunology HIV Infections - prevention & control HIV Infections - virology HIV-1 HIV-1 - immunology Human immunodeficiency virus 1 Humans Immunity, Humoral Immunization, Passive Infection Infectious Disease Neutralization Tests Primates Protein Structure, Tertiary Reviews Vaccine Vaccines
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