Therapeutic Deep Brain Stimulation in Parkinsonian Rats Directly Influences Motor Cortex

Much recent discussion about the origin of Parkinsonian symptoms has centered around the idea that they arise with the increase of beta frequency waves in the EEG. This activity may be closely related to an oscillation between subthalamic nucleus (STN) and globus pallidus. Since STN is the target of...

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Veröffentlicht in:	Neuron (Cambridge, Mass.) Mass.), 2012-12, Vol.76 (5), p.1030-1041
Hauptverfasser:	Li, Qian, Ke, Ya, Chan, Danny C.W., Qian, Zhong-Ming, Yung, Ken K.L., Ko, Ho, Arbuthnott, Gordon W., Yung, Wing-Ho
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - physiology Adrenergic Agents - toxicity Afferent Pathways - physiology Animals Antiparkinson Agents - therapeutic use Apomorphine - therapeutic use Basal ganglia Biophysics Brain Mapping Brain research Central nervous system diseases Cortex (motor) Deep brain stimulation Deep Brain Stimulation - methods Disease Models, Animal Dominance Dopamine EEG Electrical stimuli Electrodes Electrodes, Implanted Electroencephalography Electrophysiological recording Eusebio Evoked Potentials, Motor - physiology Experiments Firing pattern Fourier transforms Functional Laterality Globus pallidus Locomotion - physiology Male Medial Forebrain Bundle - drug effects Medial Forebrain Bundle - physiopathology Motor Cortex - pathology Motor Cortex - physiopathology Motor task performance Movement disorders Neurons Neurons - drug effects Neurons - physiology Oscillations Oxidopamine - toxicity Parkinson's disease Parkinsonian Disorders - chemically induced Parkinsonian Disorders - physiopathology Parkinsonian Disorders - therapy Rats Rats, Sprague-Dawley Rhythms Rodents Solitary tract nucleus Statistics as Topic Stochasticity Studies subthalamic nucleus Subthalamic Nucleus - physiology
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