Self-formation of layered neural structures in three-dimensional culture of ES cells

Highlights ► Rostral forebrain is a default differentiation direction of ES cell culture. ► ES cell-derived telencephalic progenitors generate cortical neurons. ► Sequential commitments of cortical neurons also occur in ES cell culture. ► 3D ES cell culture enables self-formation of layered cortical...

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Veröffentlicht in:	Current opinion in neurobiology 2012-10, Vol.22 (5), p.768-777
Hauptverfasser:	Eiraku, Mototsugu, Sasai, Yoshiki
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Culture Techniques - methods Cell Differentiation Cells, Cultured Embryonic Stem Cells - physiology Humans Neurogenesis - physiology Neurology Psychiatry
Online-Zugang:	Volltext
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