Self-formation of layered neural structures in three-dimensional culture of ES cells
Highlights ► Rostral forebrain is a default differentiation direction of ES cell culture. ► ES cell-derived telencephalic progenitors generate cortical neurons. ► Sequential commitments of cortical neurons also occur in ES cell culture. ► 3D ES cell culture enables self-formation of layered cortical...
Gespeichert in:
| Veröffentlicht in: | Current opinion in neurobiology 2012-10, Vol.22 (5), p.768-777 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 777 |
|---|---|
| container_issue | 5 |
| container_start_page | 768 |
| container_title | Current opinion in neurobiology |
| container_volume | 22 |
| creator | Eiraku, Mototsugu Sasai, Yoshiki |
| description | Highlights ► Rostral forebrain is a default differentiation direction of ES cell culture. ► ES cell-derived telencephalic progenitors generate cortical neurons. ► Sequential commitments of cortical neurons also occur in ES cell culture. ► 3D ES cell culture enables self-formation of layered cortical and retinal structure. ► Optic cup structure is also formed by self-organization in 3D ES cell culture. |
| doi_str_mv | 10.1016/j.conb.2012.02.005 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1272718569</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S095943881200027X</els_id><sourcerecordid>1126616825</sourcerecordid><originalsourceid>FETCH-LOGICAL-c510t-24723b7fca0b41b357feaaf61e0ba8ea120f4368e9e79b3984c04df3ade5a6453</originalsourceid><addsrcrecordid>eNqFkU9r3DAQxUVJabZpv0APwcdcvB1JtixDKYSQ_oFAD5tCb0KWR1Qb2UokO7DfvhKb5tBDCgM6zHsPze8R8oHClgIVH_dbE-Zhy4CyLeSB9hXZUNnxWkjJTsgG-ravGy7lKXmb0h4ABJf8DTllrIG2l_2G3O7Q29qGOOnFhbkKtvL6gBHHasY1al-lJa5mWSOmys3V8jsi1qObcE5Zn_dm9WVbnNe7yqD36R15bbVP-P7pPSM_v1zfXn2rb358_X51eVOblsJSs6ZjfOis0TA0dOBtZ1FrKyjCoCVqysA2XEjssesH3svGQDNarkdstWhafkYujrn3MTysmBY1uVR-oGcMa1KUdayjshX9_6WUCUGFZCWVHaUmhpQiWnUf3aTjQVFQBbzaqwJeFfAK8kAxnT_lr8OE47PlL-ks-HQUYAby6DCqZBzOBkcX0SxqDO7l_M__2I13szPa3-EB0z6sMZeR71ApG9SuVF-azwwBWPeL_wFYtqlh</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1126616825</pqid></control><display><type>article</type><title>Self-formation of layered neural structures in three-dimensional culture of ES cells</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>Eiraku, Mototsugu ; Sasai, Yoshiki</creator><creatorcontrib>Eiraku, Mototsugu ; Sasai, Yoshiki</creatorcontrib><description>Highlights ► Rostral forebrain is a default differentiation direction of ES cell culture. ► ES cell-derived telencephalic progenitors generate cortical neurons. ► Sequential commitments of cortical neurons also occur in ES cell culture. ► 3D ES cell culture enables self-formation of layered cortical and retinal structure. ► Optic cup structure is also formed by self-organization in 3D ES cell culture.</description><identifier>ISSN: 0959-4388</identifier><identifier>EISSN: 1873-6882</identifier><identifier>DOI: 10.1016/j.conb.2012.02.005</identifier><identifier>PMID: 22405989</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Animals ; Cell Culture Techniques - methods ; Cell Differentiation ; Cells, Cultured ; Embryonic Stem Cells - physiology ; Humans ; Neurogenesis - physiology ; Neurology ; Psychiatry</subject><ispartof>Current opinion in neurobiology, 2012-10, Vol.22 (5), p.768-777</ispartof><rights>Elsevier Ltd</rights><rights>2012 Elsevier Ltd</rights><rights>Copyright © 2012 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c510t-24723b7fca0b41b357feaaf61e0ba8ea120f4368e9e79b3984c04df3ade5a6453</citedby><cites>FETCH-LOGICAL-c510t-24723b7fca0b41b357feaaf61e0ba8ea120f4368e9e79b3984c04df3ade5a6453</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.conb.2012.02.005$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3548,27922,27923,45993</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22405989$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Eiraku, Mototsugu</creatorcontrib><creatorcontrib>Sasai, Yoshiki</creatorcontrib><title>Self-formation of layered neural structures in three-dimensional culture of ES cells</title><title>Current opinion in neurobiology</title><addtitle>Curr Opin Neurobiol</addtitle><description>Highlights ► Rostral forebrain is a default differentiation direction of ES cell culture. ► ES cell-derived telencephalic progenitors generate cortical neurons. ► Sequential commitments of cortical neurons also occur in ES cell culture. ► 3D ES cell culture enables self-formation of layered cortical and retinal structure. ► Optic cup structure is also formed by self-organization in 3D ES cell culture.</description><subject>Animals</subject><subject>Cell Culture Techniques - methods</subject><subject>Cell Differentiation</subject><subject>Cells, Cultured</subject><subject>Embryonic Stem Cells - physiology</subject><subject>Humans</subject><subject>Neurogenesis - physiology</subject><subject>Neurology</subject><subject>Psychiatry</subject><issn>0959-4388</issn><issn>1873-6882</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU9r3DAQxUVJabZpv0APwcdcvB1JtixDKYSQ_oFAD5tCb0KWR1Qb2UokO7DfvhKb5tBDCgM6zHsPze8R8oHClgIVH_dbE-Zhy4CyLeSB9hXZUNnxWkjJTsgG-ravGy7lKXmb0h4ABJf8DTllrIG2l_2G3O7Q29qGOOnFhbkKtvL6gBHHasY1al-lJa5mWSOmys3V8jsi1qObcE5Zn_dm9WVbnNe7yqD36R15bbVP-P7pPSM_v1zfXn2rb358_X51eVOblsJSs6ZjfOis0TA0dOBtZ1FrKyjCoCVqysA2XEjssesH3svGQDNarkdstWhafkYujrn3MTysmBY1uVR-oGcMa1KUdayjshX9_6WUCUGFZCWVHaUmhpQiWnUf3aTjQVFQBbzaqwJeFfAK8kAxnT_lr8OE47PlL-ks-HQUYAby6DCqZBzOBkcX0SxqDO7l_M__2I13szPa3-EB0z6sMZeR71ApG9SuVF-azwwBWPeL_wFYtqlh</recordid><startdate>20121001</startdate><enddate>20121001</enddate><creator>Eiraku, Mototsugu</creator><creator>Sasai, Yoshiki</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7TK</scope></search><sort><creationdate>20121001</creationdate><title>Self-formation of layered neural structures in three-dimensional culture of ES cells</title><author>Eiraku, Mototsugu ; Sasai, Yoshiki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c510t-24723b7fca0b41b357feaaf61e0ba8ea120f4368e9e79b3984c04df3ade5a6453</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Animals</topic><topic>Cell Culture Techniques - methods</topic><topic>Cell Differentiation</topic><topic>Cells, Cultured</topic><topic>Embryonic Stem Cells - physiology</topic><topic>Humans</topic><topic>Neurogenesis - physiology</topic><topic>Neurology</topic><topic>Psychiatry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Eiraku, Mototsugu</creatorcontrib><creatorcontrib>Sasai, Yoshiki</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Neurosciences Abstracts</collection><jtitle>Current opinion in neurobiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Eiraku, Mototsugu</au><au>Sasai, Yoshiki</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Self-formation of layered neural structures in three-dimensional culture of ES cells</atitle><jtitle>Current opinion in neurobiology</jtitle><addtitle>Curr Opin Neurobiol</addtitle><date>2012-10-01</date><risdate>2012</risdate><volume>22</volume><issue>5</issue><spage>768</spage><epage>777</epage><pages>768-777</pages><issn>0959-4388</issn><eissn>1873-6882</eissn><abstract>Highlights ► Rostral forebrain is a default differentiation direction of ES cell culture. ► ES cell-derived telencephalic progenitors generate cortical neurons. ► Sequential commitments of cortical neurons also occur in ES cell culture. ► 3D ES cell culture enables self-formation of layered cortical and retinal structure. ► Optic cup structure is also formed by self-organization in 3D ES cell culture.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>22405989</pmid><doi>10.1016/j.conb.2012.02.005</doi><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0959-4388 |
| ispartof | Current opinion in neurobiology, 2012-10, Vol.22 (5), p.768-777 |
| issn | 0959-4388 1873-6882 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1272718569 |
| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Animals Cell Culture Techniques - methods Cell Differentiation Cells, Cultured Embryonic Stem Cells - physiology Humans Neurogenesis - physiology Neurology Psychiatry |
| title | Self-formation of layered neural structures in three-dimensional culture of ES cells |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-14T08%3A29%3A41IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Self-formation%20of%20layered%20neural%20structures%20in%20three-dimensional%20culture%20of%20ES%20cells&rft.jtitle=Current%20opinion%20in%20neurobiology&rft.au=Eiraku,%20Mototsugu&rft.date=2012-10-01&rft.volume=22&rft.issue=5&rft.spage=768&rft.epage=777&rft.pages=768-777&rft.issn=0959-4388&rft.eissn=1873-6882&rft_id=info:doi/10.1016/j.conb.2012.02.005&rft_dat=%3Cproquest_cross%3E1126616825%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1126616825&rft_id=info:pmid/22405989&rft_els_id=S095943881200027X&rfr_iscdi=true |