Toxic effects of microcystin-LR on the reproductive system of male Rana nigromaculata in vitro

► Microcystin-LR (MCLR) can induce reproductive toxic effects on male Rana nigromaculata in vitro. ► MCLR can induce distention of mitochondria, endoplasmic reticulum, and Golgi apparatus in the testis of R. nigromaculata. ► The antioxidant defense system of the testis in R. nigromaculata can quickl...

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Veröffentlicht in:	Aquatic toxicology 2013-01, Vol.126 (15), p.283-290
Hauptverfasser:	Zhang, Hangjun, Cai, Chenchen, Wu, Yingzhu, Ye, Binhui, Han, Li, Shou, Xiaolu, Wang, Mengdi, Wang, Jia, Jia, Xiuying
Format:	Artikel
Sprache:	eng
Schlagworte:	Amphibia. Reptilia amphibians Animal, plant and microbial ecology Animals Applied ecology Biological and medical sciences catalase color Ecotoxicology, biological effects of pollution endoplasmic reticulum Enzyme Activation - drug effects Enzymes - metabolism Frog Fundamental and applied biological sciences. Psychology Gene Expression Regulation - drug effects General aspects genes Genitalia, Male - drug effects glutathione glutathione transferase Golgi apparatus Male malondialdehyde Malondialdehyde - metabolism MCLR microcystin-LR Microcystins - toxicity Microscopy, Electron, Transmission mitochondria oxidative stress quantitative polymerase chain reaction Rana Rana nigromaculata Ranidae reactive oxygen species Reactive Oxygen Species - metabolism Reproductive toxicity Sertoli Cells - drug effects sperm motility spermatozoa Spermatozoa - drug effects superoxide dismutase testes Testis toxicity unspecific monooxygenase Vertebrates: general zoology, morphology, phylogeny, systematics, cytogenetics, geographical distribution Water Pollutants, Chemical - toxicity
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