Effect of hormone replacement therapy on cardiovascular events in recently postmenopausal women: randomised trial

Objective To investigate the long term effect of hormone replacement therapy on cardiovascular outcomes in recently postmenopausal women.Design Open label, randomised controlled trial.Setting Denmark, 1990-93.Participants 1006 healthy women aged 45-58 who were recently postmenopausal or had perimeno...

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Veröffentlicht in:	BMJ (Online) 2012-10, Vol.345 (7881), p.16-16
Hauptverfasser:	Schierbeck, Louise Lind, Rejnmark, Lars, Tofteng, Charlotte Landbo, Stilgren, Lis, Eiken, Pia, Mosekilde, Leif, Køber, Lars, Jensen, Jens-Erik Beck
Format:	Artikel
Sprache:	eng
Schlagworte:	17β-Estradiol Acetic acid Breast cancer Breast Neoplasms - mortality Cardiology Cardiovascular disease Cerebral infarction Contraceptives, Oral, Synthetic - therapeutic use Denmark - epidemiology Endocrinology Estradiol - therapeutic use Estrogens Estrogens - therapeutic use Evidence-based medicine Female Follicle Stimulating Hormone - blood Follow-Up Studies Health risk assessment Heart Heart diseases Heart Failure - mortality Hormone replacement therapy Hormone Replacement Therapy - adverse effects Hormone Replacement Therapy - methods Hormone Replacement Therapy - mortality Hospitalization Humans Hysterectomy Menopause Middle Aged Mortality Myocardial infarction Myocardial Infarction - mortality Neoplasms - mortality Norethindrone - analogs & derivatives Norethindrone - therapeutic use Post-menopause Postmenopause Prospective Studies Risk Sensitivity analysis Stroke Stroke - epidemiology Strokes Thromboembolism Thrombosis Time Factors Treatment Outcome Uterus Venous thrombosis Venous Thrombosis - mortality Womens health
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