Enhancement of Initial Equivalency for Protein Structure Alignment Based on Encoded Local Structures

Most alignment algorithms find an initial equivalent residue pair followed by an iterative optimization process to explore better near-optimal alignments in the surrounding solution space of the initial alignment. It plays a decisive role in determining the alignment quality since a poor initial ali...

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Veröffentlicht in:	IEEE journal of biomedical and health informatics 2012-11, Vol.16 (6), p.1185-1192
Hauptverfasser:	Hung, K., Jui-Chih Wang, Cheng-Wei Chen, Cheng-Long Chuang, Kun-Nan Tsai, Chung-Ming Chen
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithm design and analysis Algorithms Amino acids Computational Biology - methods Initial equivalency Models, Molecular Optimization Protein engineering Protein Structure, Secondary Proteins Proteins - chemistry secondary structure Sequence Alignment - methods Statistical analysis structural alphabet structure alignment Studies Vectors
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