Genetics and infectivity of H5N1 highly pathogenic avian influenza viruses isolated from chickens and wild birds in Japan during 2010–11

► PA gene of all of Japan isolates was found in wild bird strains except H5N1 HPAIVs. ► Survivability of chickens infected with chicken and wild bird strains was different. ► Less viral transmission would correlate with less viral excretion and adaptation. Outbreaks of H5N1 subtype highly pathogenic...

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Veröffentlicht in:	Virus research 2012-12, Vol.170 (1-2), p.109-117
Hauptverfasser:	Uchida, Yuko, Suzuki, Yasushi, Shirakura, Masayuki, Kawaguchi, Akira, Nobusawa, Eri, Tanikawa, Taichiro, Hikono, Hirokazu, Takemae, Nobuhiro, Mase, Masaji, Kanehira, Katsushi, Hayashi, Tsuyoshi, Tagawa, Yuichi, Tashiro, Masato, Saito, Takehiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptations Amino Acid Substitution ancestry Animals Aves Avian influenza virus birds Birds - virology Chicken chickens Chickens - virology Clade 2.3.2.1 Disease transmission ducks Evolution Evolutionary genetics Excretion Fowl plague genes Genetic analysis genetic techniques and protocols H5N1 subtype highly pathogenic avian influenza Hemagglutination Inhibition Tests Hemagglutinin Glycoproteins, Influenza Virus - chemistry Hemagglutinin Glycoproteins, Influenza Virus - genetics Infectivity Influenza A virus Influenza A Virus, H5N1 Subtype - genetics Influenza A Virus, H5N1 Subtype - immunology Influenza A Virus, H5N1 Subtype - pathogenicity Influenza in Birds - epidemiology Influenza in Birds - virology mandarins Models, Molecular Molecular Sequence Data PA gene segment pathogenicity Phylogeny Protein Conformation Survival Virus Replication viruses Wild bird wild birds
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