Design, synthesis and bioevalution of novel benzamides derivatives as HDAC inhibitors

A series of novel benzamides derivatives was designed and synthesized as HDAC inhibitors. A series of novel benzamides derivatives was designed and synthesized as HDAC inhibitors. Exploration of the structure–activity relationships resulted in compounds that are potent in vitro. In addition, the bes...

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Veröffentlicht in:Bioorganic & medicinal chemistry letters 2013-01, Vol.23 (1), p.179-182
Hauptverfasser: Li, Yanyang, Zhou, Yan, Qian, Pengyu, Wang, Yongzhen, Jiang, Falong, Yao, Zhenglin, Hu, Wenxiang, Zhao, Yanjin, Li, Shuxin
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Sprache:eng
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