Rotavirus vaccine trial in Jamaica
Worldwide, rotaviruses have been a significant cause of dehydrating gastroenteritis. This contributed to increased infant morbidity and mortality in Jamaica. We enrolled 1804 Jamaican infants in the international randomized, placebo-controlled, pentavalent (G1, G2, G3, G4 and P1) rotavirus vaccine t...
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| Veröffentlicht in: | West Indian medical journal 2012-07, Vol.61 (4), p.405-407 |
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| container_title | West Indian medical journal |
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| creator | Christie, C D C Duncan, N D |
| description | Worldwide, rotaviruses have been a significant cause of dehydrating gastroenteritis. This contributed to increased infant morbidity and mortality in Jamaica. We enrolled 1804 Jamaican infants in the international randomized, placebo-controlled, pentavalent (G1, G2, G3, G4 and P1) rotavirus vaccine trial. This pentavalent vaccine was found to significantly reduce rotavirus gastroenteritis attributable emergency room visits and hospitalizations, without increasing the rates of intussusception, or other serious adverse events in Jamaican infants. It is recommended that the rotavirus vaccine be included in Jamaica's National Immunization Programme in accordance with recommendations from the World Health Organization. |
| doi_str_mv | 10.7727/wimj.2012.219 |
| format | Article |
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This contributed to increased infant morbidity and mortality in Jamaica. We enrolled 1804 Jamaican infants in the international randomized, placebo-controlled, pentavalent (G1, G2, G3, G4 and P1) rotavirus vaccine trial. This pentavalent vaccine was found to significantly reduce rotavirus gastroenteritis attributable emergency room visits and hospitalizations, without increasing the rates of intussusception, or other serious adverse events in Jamaican infants. It is recommended that the rotavirus vaccine be included in Jamaica's National Immunization Programme in accordance with recommendations from the World Health Organization.</description><identifier>ISSN: 0043-3144</identifier><identifier>DOI: 10.7727/wimj.2012.219</identifier><identifier>PMID: 23240476</identifier><language>eng</language><publisher>Jamaica</publisher><subject>Disease Outbreaks ; Environmental Exposure ; Gastroenteritis - virology ; Humans ; Jamaica ; Rotavirus Infections - prevention & control ; Rotavirus Vaccines - therapeutic use ; Vaccines, Attenuated - therapeutic use</subject><ispartof>West Indian medical journal, 2012-07, Vol.61 (4), p.405-407</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c326t-6ad0f9b74d98921fec1dd346eaf0a80aa498e2f1f2f1c3549d8e9060c8ee3b6f3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23240476$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Christie, C D C</creatorcontrib><creatorcontrib>Duncan, N D</creatorcontrib><title>Rotavirus vaccine trial in Jamaica</title><title>West Indian medical journal</title><addtitle>West Indian Med J</addtitle><description>Worldwide, rotaviruses have been a significant cause of dehydrating gastroenteritis. This contributed to increased infant morbidity and mortality in Jamaica. We enrolled 1804 Jamaican infants in the international randomized, placebo-controlled, pentavalent (G1, G2, G3, G4 and P1) rotavirus vaccine trial. This pentavalent vaccine was found to significantly reduce rotavirus gastroenteritis attributable emergency room visits and hospitalizations, without increasing the rates of intussusception, or other serious adverse events in Jamaican infants. It is recommended that the rotavirus vaccine be included in Jamaica's National Immunization Programme in accordance with recommendations from the World Health Organization.</description><subject>Disease Outbreaks</subject><subject>Environmental Exposure</subject><subject>Gastroenteritis - virology</subject><subject>Humans</subject><subject>Jamaica</subject><subject>Rotavirus Infections - prevention & control</subject><subject>Rotavirus Vaccines - therapeutic use</subject><subject>Vaccines, Attenuated - therapeutic use</subject><issn>0043-3144</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kEtLw0AUhWeh2FpdupXgyk3inUcnmaUUnxQE0fVwO7kDU5KmziQV_70prS4OZ_NxOHyMXXEoylKUd9-hXRcCuCgENydsCqBkLrlSE3ae0hpAS67hjE2EFApUqafs5r3rcRfikLIdOhc2lPUxYJOFTfaKLQaHF-zUY5Po8tgz9vn48LF4zpdvTy-L-2XupNB9rrEGb1alqk1lBPfkeF1LpQk9YAWIylQkPPdjnJwrU1dkQIOriORKezljt4fdbey-Bkq9bUNy1DS4oW5Ilo-fBedzmI9ofkBd7FKK5O02hhbjj-Vg9yrsXoXdq7CjipG_Pk4Pq5bqf_rPg_wFkrhbLg</recordid><startdate>20120701</startdate><enddate>20120701</enddate><creator>Christie, C D C</creator><creator>Duncan, N D</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20120701</creationdate><title>Rotavirus vaccine trial in Jamaica</title><author>Christie, C D C ; Duncan, N D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c326t-6ad0f9b74d98921fec1dd346eaf0a80aa498e2f1f2f1c3549d8e9060c8ee3b6f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Disease Outbreaks</topic><topic>Environmental Exposure</topic><topic>Gastroenteritis - virology</topic><topic>Humans</topic><topic>Jamaica</topic><topic>Rotavirus Infections - prevention & control</topic><topic>Rotavirus Vaccines - therapeutic use</topic><topic>Vaccines, Attenuated - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Christie, C D C</creatorcontrib><creatorcontrib>Duncan, N D</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>West Indian medical journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Christie, C D C</au><au>Duncan, N D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Rotavirus vaccine trial in Jamaica</atitle><jtitle>West Indian medical journal</jtitle><addtitle>West Indian Med J</addtitle><date>2012-07-01</date><risdate>2012</risdate><volume>61</volume><issue>4</issue><spage>405</spage><epage>407</epage><pages>405-407</pages><issn>0043-3144</issn><abstract>Worldwide, rotaviruses have been a significant cause of dehydrating gastroenteritis. 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| fulltext | fulltext |
| identifier | ISSN: 0043-3144 |
| ispartof | West Indian medical journal, 2012-07, Vol.61 (4), p.405-407 |
| issn | 0043-3144 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1240211505 |
| source | MEDLINE; Alma/SFX Local Collection; EZB Electronic Journals Library |
| subjects | Disease Outbreaks Environmental Exposure Gastroenteritis - virology Humans Jamaica Rotavirus Infections - prevention & control Rotavirus Vaccines - therapeutic use Vaccines, Attenuated - therapeutic use |
| title | Rotavirus vaccine trial in Jamaica |
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