Decreased interferon-α and interferon-β production in obesity and expression of suppressor of cytokine signaling

Abstract Objective We analyzed the interferon-α (IFN-α), IFN-β, and proinflammatory responses induced by Toll-like receptor (TLR) ligands in peripheral blood mononuclear cells (PBMCs) from obese subjects and their association with suppressor of cytokine signaling-1 (SOCS1) and SOCS3 expression. Meth...

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Veröffentlicht in:	Nutrition (Burbank, Los Angeles County, Calif.) Los Angeles County, Calif.), 2013, Vol.29 (1), p.207-212
Hauptverfasser:	TERAN-CABANILLAS, Eli, MONTALVO-CORRAL, Maricela, CAIRE-JUVERA, Graciela, MOYA-CAMARENA, Silvia Y, HERNANDEZ, Jesus
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biological and medical sciences Cross-Sectional Studies Feeding. Feeding behavior Female Fundamental and applied biological sciences. Psychology Gastroenterology and Hepatology Gene Expression Humans Interferon Interferon-alpha - biosynthesis Interferon-alpha - blood Interferon-beta - biosynthesis Interferon-beta - blood Interleukin-6 - blood Ligands Male Medical sciences Metabolic diseases Middle Aged Obesity Obesity - blood Obesity - genetics Obesity - immunology RNA, Messenger - blood RNA, Messenger - genetics Signal Transduction - immunology Suppressor of Cytokine Signaling 1 Protein Suppressor of Cytokine Signaling 3 Protein Suppressor of Cytokine Signaling Proteins - blood Suppressor of Cytokine Signaling Proteins - genetics suppressor of cytokine signaling-3 Toll-like receptor Toll-like receptor-3 Toll-Like Receptors - metabolism Vertebrates: anatomy and physiology, studies on body, several organs or systems Young Adult
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