Synthesis and properties of squaraine-modified DNA

The incorporation of squaraines into DNA via the phosphoramidite approach is described. High molar absorptivity, environment-sensitive fluorescence properties and intense CD effects render squaraines valuable building blocks for DNA-based optical probes and nanostructures.

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Veröffentlicht in:Organic & biomolecular chemistry 2012-12, Vol.10 (45), p.8944-8947
Hauptverfasser: Markova, Larysa I, Malinovskii, Vladimir L, Patsenker, Leonid D, Häner, Robert
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container_issue 45
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container_title Organic & biomolecular chemistry
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creator Markova, Larysa I
Malinovskii, Vladimir L
Patsenker, Leonid D
Häner, Robert
description The incorporation of squaraines into DNA via the phosphoramidite approach is described. High molar absorptivity, environment-sensitive fluorescence properties and intense CD effects render squaraines valuable building blocks for DNA-based optical probes and nanostructures.
doi_str_mv 10.1039/c2ob26787j
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source MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection
subjects Chemistry Techniques, Synthetic
Cyclobutanes - chemistry
DNA
DNA - chemical synthesis
DNA - chemistry
Fluorescence
Fluorescent indicators
Oligodeoxyribonucleotides - chemical synthesis
Oligodeoxyribonucleotides - chemistry
Optical Phenomena
Organophosphorus Compounds - chemistry
Phenols - chemistry
Spectrum Analysis
title Synthesis and properties of squaraine-modified DNA
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