Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients

Bladder cancer is a common urologic cancer whose incidence continues to rise annually. Urinary microparticles are an attractive material for noninvasive bladder cancer biomarker discovery. In this study, we applied isotopic dimethylation labeling coupled with liquid chromatography-tandem mass spectr...

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Veröffentlicht in:	Journal of proteome research 2012-12, Vol.11 (12), p.5611-5629
Hauptverfasser:	Chen, Chien-Lun, Lai, Yue-Fan, Tang, Petrus, Chien, Kun-Yi, Yu, Jau-Song, Tsai, Cheng-Han, Chen, Hsiao-Wei, Wu, Chih-Ching, Chung, Ting, Hsu, Chia-Wei, Chen, Chi-De, Chang, Yu-Sun, Chang, Phei-Lang, Chen, Yi-Ting
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Amino Acid Sequence Antigens, Neoplasm - urine Area Under Curve Biomarkers, Tumor - urine Case-Control Studies Cell Adhesion Molecules - urine Chromatography, Liquid - methods Enzyme-Linked Immunosorbent Assay Exosomes - chemistry Female Hematuria - diagnosis Hernia - diagnosis Humans Isotope Labeling Male Mass Spectrometry - methods Middle Aged Molecular Sequence Data Neoplasm Proteins - urine Proteome - analysis Proteomics - methods Reproducibility of Results Urinary Bladder Neoplasms - chemistry Urinary Bladder Neoplasms - diagnosis
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