Analysis of transmitted drug resistance in Spain in the years 2007–2010 documents a decline in mutations to the non-nucleoside drug class

We have studied transmitted drug resistance (TDR) in 1.864 antiretroviral-naïve patients entering CoRIS (Spain) during 2007–2010. An overall 8.58% TDR was observed (3.92%, nucleoside reverse transcriptase inhibitors (NRTIs); 3.86%, non-nucleoside reverse transcriptase inhibitors (NNRTIs); 2.31%, pro...

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Veröffentlicht in:	Clinical microbiology and infection 2012-11, Vol.18 (11), p.E485-E490
Hauptverfasser:	Monge, S., Guillot, V., Alvarez, M., Peña, A., Viciana, P., García-Bujalance, S., Pérez Elias, M.J., Iribarren, J.A., Gutiérrez, F., Itziar Casado, M., Garcia, F., CoRIS
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anti-Retroviral Agents - administration & dosage Anti-Retroviral Agents - pharmacology CoRIS Drug Resistance, Viral Female Genotype HIV HIV - drug effects HIV - isolation & purification HIV Infections - epidemiology HIV Infections - transmission HIV Infections - virology HIV Reverse Transcriptase - genetics Humans Male Mutation, Missense non-B subtypes Nucleosides - administration & dosage Nucleosides - pharmacology Reverse Transcriptase Inhibitors - administration & dosage Reverse Transcriptase Inhibitors - pharmacology Spain - epidemiology transmitted drug resistance
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