Feasibility of landiolol and bisoprolol for prevention of atrial fibrillation after coronary artery bypass grafting: A pilot study

Background We previously performed a trial of intravenous landiolol hydrochloride during and after cardiac surgery (the PASCAL trial) and demonstrated a preventive effect on postoperative atrial fibrillation (AF). In the present study, we investigated the efficacy of increasing the dose and administ...

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Veröffentlicht in:	The Journal of thoracic and cardiovascular surgery 2012-11, Vol.144 (5), p.1241-1248
Hauptverfasser:	Sezai, Akira, MD, PhD, Nakai, Tishiko, MD, PhD, Hata, Mitsumasa, MD, PhD, Yoshitake, Isamu, MD, PhD, Shiono, Motomi, MD, PhD, Kunimoto, Satoshi, MD, PhD, Hirayama, Atsushi, MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adrenergic beta-Antagonists - administration & dosage Aged Aged, 80 and over Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anti-Arrhythmia Agents - administration & dosage Anti-Inflammatory Agents - administration & dosage Antioxidants - administration & dosage Arginine - analogs & derivatives Arginine - blood Atrial Fibrillation - blood Atrial Fibrillation - etiology Atrial Fibrillation - mortality Atrial Fibrillation - physiopathology Atrial Fibrillation - prevention & control Biological and medical sciences Biomarkers - blood Bisoprolol - administration & dosage C-Reactive Protein - metabolism Cardiac dysrhythmias Cardiology. Vascular system Cardiothoracic Surgery Coronary Artery Bypass - adverse effects Coronary Artery Bypass - mortality Coronary heart disease Creatine Kinase, MB Form - blood Drug Administration Schedule Fatty Acid Binding Protein 3 Fatty Acid-Binding Proteins - blood Female Heart Hemodynamics - drug effects Humans Infusions, Intravenous Japan Male Medical sciences Middle Aged Morpholines - administration & dosage Natriuretic Peptide, Brain - blood Pilot Projects Pneumology Serum Amyloid P-Component - metabolism Single-Blind Method Time Factors Treatment Outcome Troponin I - blood Urea - administration & dosage Urea - analogs & derivatives
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