Catalytic Mechanisms and Biocatalytic Applications of Aspartate and Methylaspartate Ammonia Lyases

Ammonia lyases catalyze the formation of α,β-unsaturated bonds by the elimination of ammonia from their substrates. This conceptually straightforward reaction has been the emphasis of many studies, with the main focus on the catalytic mechanism of these enzymes and/or the use of these enzymes as cat...

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Veröffentlicht in:	ACS chemical biology 2012-10, Vol.7 (10), p.1618-1628
Hauptverfasser:	de Villiers, Marianne, Puthan Veetil, Vinod, Raj, Hans, de Villiers, Jandré, Poelarends, Gerrit J
Format:	Artikel
Sprache:	eng
Schlagworte:	Ammonia - chemistry Ammonia-Lyases - chemistry Ammonia-Lyases - metabolism Aspartate Ammonia-Lyase - chemistry Aspartate Ammonia-Lyase - metabolism Bacteria - enzymology Biocatalysis Catalytic Domain Models, Molecular Protein Engineering
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