Involvement of transcription factor Ets‐1 in the expression of the α3 integrin subunit gene

The α3β1 integrin is an adhesion receptor for extracellular matrix proteins, and plays crucial roles in cell motility, proliferation, and differentiation. The aberrant expression of this adhesion molecule on tumor cells is frequently associated with their malignant behaviors. We previously reported...

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Veröffentlicht in:	The FEBS journal 2012-12, Vol.279 (24), p.4535-4546
Hauptverfasser:	Kamoshida, Go, Matsuda, Ayaka, Katabami, Kouji, Kato, Takumi, Mizuno, Hiromi, Sekine, Wakana, Oku, Teruaki, Itoh, Saotomo, Tsuiji, Makoto, Hattori, Yoshiyuki, Maitani, Yoshie, Tsuji, Tsutomu
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line, Tumor Ets‐1 Gene Expression Regulation - physiology Humans integrin Integrin alpha3 - genetics promoter Proto-Oncogene Protein c-ets-1 - physiology transcription factor Transcriptional Activation - physiology Transforming Growth Factor beta1 - physiology transforming growth factor‐β Up-Regulation
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