A Naked-Eye On–Off–On Molecular “Light Switch” Based on a Reversible “Conformational Switch” of G‑Quadruplex DNA

Herein, we report a new strategy for developing an on–off–on molecular “light switch” by utilizing the pH value to control the “conformational switch” of G-quadruplex DNA. A novel ruthenium(II) complex with an emission enhancement factor of 150 was synthesized and introduced to detect the switch by...

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Veröffentlicht in:	Inorganic chemistry 2012-12, Vol.51 (23), p.12591-12593
Hauptverfasser:	Yao, Jun-Liang, Gao, Xing, Sun, Wenliang, Fan, Xue-Zhong, Shi, Shuo, Yao, Tian-Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	Circular Dichroism DNA - chemistry Fluorescence G-Quadruplexes Hydrogen-Ion Concentration Models, Molecular Molecular Conformation Organometallic Compounds - chemical synthesis Organometallic Compounds - chemistry Quantum Theory Ruthenium - chemistry
Online-Zugang:	Volltext
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