Treatment of Lipoxin A(4) and its analogue on low-dose endotoxin induced preeclampsia in rat and possible mechanisms

Preeclampsia (PE) is known to represent an exaggerated maternal inflammatory response to pregnancy. Lipoxin A(4) (LXA(4)), considered as an endogenous stop signal in inflammation, has been extensively studied pre clinically for its inflammatory pro-resolving effects. Thus, in the current study, we t...

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Veröffentlicht in:	Reproductive toxicology (Elmsford, N.Y.) N.Y.), 2012-12, Vol.34 (4), p.677-685
Hauptverfasser:	Lin, Feng, Zeng, Pan, Xu, Zhangye, Ye, Duyun, Yu, Xiaofang, Wang, Ni, Tang, Jie, Zhou, Ye, Huang, Yinping
Format:	Artikel
Sprache:	eng
Schlagworte:	Albuminuria - chemically induced Albuminuria - drug therapy Albuminuria - physiopathology Animals Anti-Inflammatory Agents - pharmacology Anti-Inflammatory Agents - therapeutic use Apoptosis - drug effects Blood Pressure - drug effects Cell Line Cell Proliferation - drug effects Cytokines - genetics Female Heptanoic Acids - pharmacology Heptanoic Acids - therapeutic use Humans Lipopolysaccharides Lipoxins - pharmacology Lipoxins - therapeutic use Pre-Eclampsia - chemically induced Pre-Eclampsia - drug therapy Pre-Eclampsia - physiopathology Pregnancy Rats Rats, Sprague-Dawley RNA, Messenger - metabolism
Online-Zugang:	Volltext
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