Association of IRS-1 and IRS-2 genes polymorphisms with polycystic ovary syndrome: a meta-analysis

Insulin resistance (IR) plays an important role in the pathogenesis of polycystic ovary syndrome (PCOS) which is a common disorder in premenopausal women. The association between the single nucleotide polymorphisms (SNPs) of insulin receptor substrate (IRS) gene and PCOS in several populations has b...

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Veröffentlicht in:	Endocrine Journal 2012, Vol.59(7), pp.601-609
Hauptverfasser:	Ruan, Yuan, Ma, Jianhua, Xie, Xiaojing
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Substitution - physiology Arginine - genetics Aspartic Acid - genetics Case-Control Studies Female Gene Frequency Genotype Geography Glycine - genetics Humans Insulin receptor substrate Insulin Receptor Substrate Proteins - genetics Meta-analysis Polycystic ovary syndrome Polycystic Ovary Syndrome - epidemiology Polycystic Ovary Syndrome - ethnology Polycystic Ovary Syndrome - genetics Polymorphism, Single Nucleotide - physiology Polymorphisms
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