Full evaporation dynamic headspace in combination with selectable one-dimensional/two-dimensional gas chromatography–mass spectrometry for the determination of suspected fragrance allergens in cosmetic products

► We applied selectable 1D/2D GC–MS for the allergen analysis in perfume samples. ► No hardware changes are needed when switching between 1D and 2D analysis. ► Full evaporation DHS is used for samples containing non-volatile matrix compounds. ► A single instrument configuration is used for 4 classes...

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Veröffentlicht in:	Journal of Chromatography A 2012-09, Vol.1255, p.207-215
Hauptverfasser:	Devos, Christophe, Ochiai, Nobuo, Sasamoto, Kikuo, Sandra, Pat, David, Frank
Format:	Artikel
Sprache:	eng
Schlagworte:	allergens Allergens - analysis Allergens - isolation & purification Chemical Fractionation - instrumentation Chemical Fractionation - methods Cosmetics Cosmetics - chemistry Dynamic headspace evaporation gas chromatography-mass spectrometry Gas Chromatography-Mass Spectrometry - methods GC–MS gels headspace analysis Heart-cutting two-dimensional GC molecular weight odor compounds Odorants - analysis odors Organic Chemicals - analysis Perfume - chemistry perfumes Reproducibility of Results Suspected fragrance allergens temperature Volatilization
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