Tail-end amphiphilic dimethylaminopyridinium-containing polymethacrylates for gene delivery

Amphiphilic dimethylaminopyridinium alkyl polymethacrylates (aPPs) were tested for gene complexation, cell cytotoxicity and in vitro gene expression for use as gene delivery agents. The aminopyridinium groups neutralized by bromide or octylsulfonate counterions were terminal moieties of side-chain s...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	New journal of chemistry 2009-01, Vol.33 (9), p.1941-1950
Hauptverfasser:	Vuillaume, Pascal Y., Brunelle, Mélanie, Bazuin, C. Géraldine, Talbot, Brian G., Bégin, André, Van Calsteren, Marie-Rose, Laurent-Lewandowski, Sylvette
Format:	Artikel
Sprache:	eng
Schlagworte:	bromides Condensation Cytotoxicity DNA Gene expression Gene transfer nanoparticles Phosphate Physicochemical properties pyridinium Spacer Transfection
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!