Proactive management of extreme prematurity: disagreement between obstetricians and neonatologists

Objective: To verify, in extremely preterm infants, if disagreement between obstetricians and neonatologists regarding proactive management is associated with early death. Study Design: Prospective cohort of 484 infants with 23 0/7 to 26 6/7 weeks, without malformations, born from January 2006 to De...

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Veröffentlicht in:Journal of perinatology 2012-12, Vol.32 (12), p.913-919
Hauptverfasser: Guinsburg, R, Branco de Almeida, M F, dos Santos Rodrigues Sadeck, L, Marba, S T M, Suppo de Souza Rugolo, L M, Luz, J H, de Andrade Lopes, J M, Martinez, F E, Procianoy, R S
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container_end_page 919
container_issue 12
container_start_page 913
container_title Journal of perinatology
container_volume 32
creator Guinsburg, R
Branco de Almeida, M F
dos Santos Rodrigues Sadeck, L
Marba, S T M
Suppo de Souza Rugolo, L M
Luz, J H
de Andrade Lopes, J M
Martinez, F E
Procianoy, R S
description Objective: To verify, in extremely preterm infants, if disagreement between obstetricians and neonatologists regarding proactive management is associated with early death. Study Design: Prospective cohort of 484 infants with 23 0/7 to 26 6/7 weeks, without malformations, born from January 2006 to December 2009 in eight Brazilian hospitals. Pro-active management was defined as indication of ⩾1 dose of antenatal steroid or cesarean section (obstetrician) and resuscitation at birth according to the international guidelines (neonatologist). Main outcome was neonatal death in the first 24 h of life. Result: Obstetricians and neonatologists disagreed in 115 (24%) patients: only neonatologists were proactive in 107 of them. Disagreement between professionals increased 2.39 times the chance of death in the first day (95% confidence interval 1.40 to 4.09), adjusted for center and maternal/neonatal clinical conditions. Conclusion: In infants with 23 to 26 weeks of gestation, disagreement between obstetricians and neonatologists, translated as lack of antenatal steroids and/or vaginal delivery, despite resuscitation procedures, increases the odds of death in the first day.
doi_str_mv 10.1038/jp.2012.28
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Study Design: Prospective cohort of 484 infants with 23 0/7 to 26 6/7 weeks, without malformations, born from January 2006 to December 2009 in eight Brazilian hospitals. Pro-active management was defined as indication of ⩾1 dose of antenatal steroid or cesarean section (obstetrician) and resuscitation at birth according to the international guidelines (neonatologist). Main outcome was neonatal death in the first 24 h of life. Result: Obstetricians and neonatologists disagreed in 115 (24%) patients: only neonatologists were proactive in 107 of them. Disagreement between professionals increased 2.39 times the chance of death in the first day (95% confidence interval 1.40 to 4.09), adjusted for center and maternal/neonatal clinical conditions. 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subjects 692/700/1750/1747
Adrenal Cortex Hormones - therapeutic use
Analysis of Variance
Beliefs, opinions and attitudes
Births
Brazil
Cardiopulmonary resuscitation
Cardiopulmonary Resuscitation - standards
Cardiopulmonary Resuscitation - trends
Care and treatment
Cesarean Section
Cohort Studies
Confidence Intervals
CPR
Death
Delivery, Obstetric - methods
Drug dosages
Female
Fetal Viability
Fetuses
Gestational Age
Health aspects
Humans
Infant Mortality - trends
Infant, Newborn
Infant, Premature
Infant, Very Low Birth Weight
Infants
Infants (Premature)
Intensive Care Units, Neonatal
Interprofessional Relations
Life Support Care - methods
Logistic Models
Male
Medicine
Medicine & Public Health
Mortality
Neonates
Neonatologists
Neonatology - standards
Neonatology - trends
Newborn babies
Obstetricians
Obstetrics - standards
Obstetrics - trends
Odds Ratio
original-article
Pediatric Surgery
Pediatrics
Practice Patterns, Physicians' - standards
Practice Patterns, Physicians' - trends
Pregnancy
Premature babies
Professionals
Prognosis
Prospective Studies
Resuscitation
Steroid hormones
Steroids
Steroids (Drugs)
Treatment Outcome
Vagina
Ventilators
title Proactive management of extreme prematurity: disagreement between obstetricians and neonatologists
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