The two-component system ChrSA is crucial for haem tolerance and interferes with HrrSA in haem-dependent gene regulation in Corynebacterium glutamicum

We recently showed that the two-component system (TCS) HrrSA plays a central role in the control of haem homeostasis in the Gram-positive soil bacterium Corynebacterium glutamicum. Here, we characterized the function of another TCS of this organism, ChrSA, which exhibits significant sequence similar...

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Veröffentlicht in:	Microbiology (Society for General Microbiology) 2012-12, Vol.158 (Pt 12), p.3020-3031
Hauptverfasser:	HEYER, Antonia, GÄTGENS, Cornelia, HENTSCHEL, Eva, KALINOWSKI, Jorn, BOTT, Michael, FRUNZKE, Julia
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Proteins - genetics Bacterial Proteins - metabolism Bacteriology Biological and medical sciences Biological Transport Corynebacterium glutamicum - drug effects Corynebacterium glutamicum - genetics Corynebacterium glutamicum - metabolism Electrophoretic Mobility Shift Assay Fundamental and applied biological sciences. Psychology Gene Deletion Gene Expression Profiling Gene Expression Regulation, Bacterial Heme - metabolism Heme - toxicity Microarray Analysis Microbiology Miscellaneous Phosphorylation Protein Processing, Post-Translational Sequence Homology, Amino Acid Transcriptional Activation
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