Suppression of MMP-9 activity by NDRG2 expression inhibits clear cell renal cell carcinoma invasion

Members of the NDRG (N-Myc downstream-regulated) gene family have been shown to play a variety of roles in human malignancies. Recently, it was shown decreased expression in clear cell renal cell carcinoma (CCRCC) and inhibited cell proliferation, but the role of the NDRG2 in CCRCC invasion has not...

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Veröffentlicht in:	Medical oncology (Northwood, London, England) London, England), 2012-12, Vol.29 (5), p.3306-3313
Hauptverfasser:	Ma, Jian-Jun, Kong, Ling-Min, Liao, Cheng-Gong, Jiang, Xue, Wang, Yong, Bao, Ting-Yi
Format:	Artikel
Sprache:	eng
Schlagworte:	Blotting, Western Carcinoma, Renal Cell - metabolism Carcinoma, Renal Cell - mortality Carcinoma, Renal Cell - pathology Female Gene Knockdown Techniques Hematology Humans Immunohistochemistry Internal Medicine Kaplan-Meier Estimate Kidney Neoplasms - metabolism Kidney Neoplasms - mortality Kidney Neoplasms - pathology Male Matrix Metalloproteinase 9 - metabolism Medicine Medicine & Public Health Middle Aged Neoplasm Invasiveness - pathology Neoplasm Staging Oncology Original Paper Pathology Real-Time Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction Tumor Suppressor Proteins - metabolism
Online-Zugang:	Volltext
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