Exocytosis is impaired in mucopolysaccharidosis IIIA mouse chromaffin cells

Highlights ► Elevated heparan sulphate storage in MPS IIIA chromaffin cells. ► Catecholamine secretion was reduced in MPS IIIA chromaffin cells. ► Fusion pore kinetics was unaltered in MPS IIIA chromaffin cells. ► Calcium entry was unaltered in MPS IIIA chromaffin cells.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neuroscience 2012-12, Vol.227, p.110-118
Hauptverfasser:	Keating, D.J, Winter, M.A, Hemsley, K.M, Mackenzie, K.D, Teo, E.H, Hopwood, J.J, Brooks, D.A, Parkinson-Lawrence, E.J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Glands - metabolism Adrenal Glands - pathology Adrenal Glands - ultrastructure Analysis of Variance Animals Biological and medical sciences Calcium - metabolism Carbohydrates (enzymatic deficiencies). Glycogenosis Carbon carbon fibre amperometry Catecholamines - metabolism Cells, Cultured chromaffin cells Chromaffin Cells - physiology Chromaffin Cells - ultrastructure Disease Models, Animal Errors of metabolism exocytosis Exocytosis - genetics Heparitin Sulfate - metabolism Lysosomes - metabolism Lysosomes - pathology Medical sciences Metabolic diseases Mice Mice, Inbred C57BL Mice, Transgenic Microscopy, Electron, Transmission mouse Mucopolysaccharidosis III - genetics Mucopolysaccharidosis III - pathology mucopolysaccharidosis IIIA Neurology neurotransmission Statistics, Nonparametric
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!