Ephrin-B stimulation of calvarial bone formation

Introduction: Ephrin‐B2 on osteoclasts was reported to promote bone formation as part of homeostasis by activating the EphB4 tyrosine kinase receptor on osteoblasts. Little is known about the role of ephrin‐B signaling to EphBs in developmental bone formation. Results: We observed expression of an e...

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Veröffentlicht in:	Developmental dynamics 2012-12, Vol.241 (12), p.1901-1910
Hauptverfasser:	Benson, M. Douglas, Opperman, Lynne A., Westerlund, Jan, Fernandez, Claudia R., San Miguel, Symone, Henkemeyer, Mark, Chenaux, George
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Differentiation - biosynthesis Antigens, Differentiation - genetics bone calvaria Cell Line ephrin-B Ephrin-B2 - genetics Ephrin-B2 - metabolism Ephrin-B2 - pharmacology Immunoglobulin Fc Fragments - genetics Immunoglobulin Fc Fragments - pharmacology Mice Mice, Knockout Organ Culture Techniques osteoblast Osteoblasts - cytology Osteoblasts - metabolism Osteogenesis - drug effects Osteogenesis - physiology Receptor, EphB1 - genetics Receptor, EphB1 - metabolism Receptor, EphB2 - genetics Receptor, EphB2 - metabolism Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - pharmacology Skull - cytology Skull - embryology
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