CaMKII, MAPK, and CREB are coactivated in identified neurons in a neocortical circuit required for performing visual shape discriminations

Current theories postulate that the essential information for specific cognitive tasks is widely dispersed in multiple forebrain areas. Nonetheless, synaptic plasticity and neural network theories hypothesize that activation of specific signaling pathways, in specific neurons, modifies synaptic stre...

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Veröffentlicht in:	Hippocampus 2012-12, Vol.22 (12), p.2276-2289
Hauptverfasser:	Zhang, Guo-Rong, Zhao, Hua, Choi, Eui M., Svestka, Michael, Wang, Xiaodan, Cook, Robert G., Geller, Alfred I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium-Calmodulin-Dependent Protein Kinase Type 2 - metabolism Cyclic AMP Response Element-Binding Protein - metabolism Enzyme Activation - physiology Extracellular Signal-Regulated MAP Kinases - metabolism Learning - physiology Neocortex - metabolism Neural Pathways - metabolism Neuronal Plasticity - physiology Neurons - metabolism Pattern Recognition, Visual - physiology postrhinal cortex protein kinase C Protein Kinase C - genetics Protein Kinase C - metabolism Rats signaling pathways synaptic plasticity Transduction, Genetic visual learning
Online-Zugang:	Volltext
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