t(11;14)(q23;q32) involving IGH and DDX6 in nodal marginal zone lymphoma

Nodal marginal zone lymphoma (NMZL) is a primary nodal B‐cell lymphoma that shares morphological and immunophenotypic characteristics with extranodal and splenic marginal zone lymphoma. Data on altered genes and signaling pathways are scarce in this rare tumor entity. To gain further insights into t...

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Veröffentlicht in:	Genes chromosomes & cancer 2013-01, Vol.52 (1), p.33-43
Hauptverfasser:	Stary, Susanne, Vinatzer, Ursula, Müllauer, Leonhard, Raderer, Markus, Birner, Peter, Streubel, Berthold
Format:	Artikel
Sprache:	eng
Schlagworte:	Caspases - metabolism Cell Line, Tumor Chromosomes, Human, Pair 11 Chromosomes, Human, Pair 14 Cytogenetic Analysis DEAD-box RNA Helicases - genetics DEAD-box RNA Helicases - metabolism DNA Copy Number Variations DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Genes, Immunoglobulin Heavy Chain Humans Loss of Heterozygosity Lymphoma, B-Cell, Marginal Zone - genetics Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein Neoplasm Proteins - metabolism NF-kappa B - metabolism Oncogene Proteins, Fusion - genetics Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins - metabolism Proto-Oncogene Proteins c-bcl-2 - genetics Proto-Oncogene Proteins c-bcl-6 Signal Transduction - genetics Translocation, Genetic Two-Hybrid System Techniques
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