Uncovering Common Principles in Protein Export of Malaria Parasites

For proliferation, the malaria parasite Plasmodium falciparum needs to modify the infected host cell extensively. To achieve this, the parasite exports proteins containing a Plasmodium export element (PEXEL) into the host cell. Phosphatidylinositol-3-phosphate binding and cleavage of the PEXEL are t...

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Veröffentlicht in:	Cell host & microbe 2012-11, Vol.12 (5), p.717-729
Hauptverfasser:	Grüring, Christof, Heiber, Arlett, Kruse, Florian, Flemming, Sven, Franci, Gianluigi, Colombo, Sara F., Fasana, Elisa, Schoeler, Hanno, Borgese, Nica, Stunnenberg, Hendrik G., Przyborski, Jude M., Gilberger, Tim-Wolf, Spielmann, Tobias
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aspartic Acid Endopeptidases - metabolism Carrier Proteins - metabolism Humans Malaria, Falciparum - metabolism Phosphatidylinositol Phosphates - metabolism Plasmodium falciparum - metabolism Protein Transport Protein Unfolding Protozoan Proteins - chemistry Protozoan Proteins - metabolism
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