The role of baroreflex activation therapy in sympathetic modulation for the treatment of resistant hypertension
In comparing BAT with renal denervation, BAT requires a more involved procedure, though the second-generation system appears to be no more involved than pacemaker placement with a small lead affixed directly to the carotid sinus through a 2.5-5 cm incision. Since there is no intravascular trauma, th...
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| Veröffentlicht in: | Heart (British Cardiac Society) 2012-12, Vol.98 (23), p.1689-1692 |
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| creator | Gassler, John P Lynch, Petra S Bisognano, John D |
| description | In comparing BAT with renal denervation, BAT requires a more involved procedure, though the second-generation system appears to be no more involved than pacemaker placement with a small lead affixed directly to the carotid sinus through a 2.5-5 cm incision. Since there is no intravascular trauma, there is no risk of secondary carotid artery stenosis occurring. [...]the BAT system can be turned off, such that in the event the patient presents with hypotension or shock, the autonomic nervous system can be allowed to respond normally to the physiologic stressor. [...]it can be adjusted upward or downward, responding to changes in the patient's overall clinical condition over the years, and can be programmed with different parameters for different therapeutic effect during day and night. |
| doi_str_mv | 10.1136/heartjnl-2012-302366 |
| format | Article |
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Since there is no intravascular trauma, there is no risk of secondary carotid artery stenosis occurring. [...]the BAT system can be turned off, such that in the event the patient presents with hypotension or shock, the autonomic nervous system can be allowed to respond normally to the physiologic stressor. [...]it can be adjusted upward or downward, responding to changes in the patient's overall clinical condition over the years, and can be programmed with different parameters for different therapeutic effect during day and night.</description><identifier>ISSN: 1355-6037</identifier><identifier>EISSN: 1468-201X</identifier><identifier>DOI: 10.1136/heartjnl-2012-302366</identifier><identifier>PMID: 22895643</identifier><language>eng</language><publisher>England: BMJ Publishing Group Ltd and British Cardiovascular Society</publisher><subject>Animals ; Baroreflex - physiology ; Blood pressure ; Blood Pressure - physiology ; Cardiac function ; Cardiology ; diastolic dysfunction ; Electric Stimulation Therapy - methods ; Heart rate ; Humans ; Hypertension ; Hypertension - physiopathology ; Hypertension - therapy ; hypertensive heart disease ; Mortality ; Nervous system ; Physiology ; Sympathetic Nervous System ; systolic dysfunction ; Veins & arteries</subject><ispartof>Heart (British Cardiac Society), 2012-12, Vol.98 (23), p.1689-1692</ispartof><rights>Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions</rights><rights>Copyright: 2012 Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b446t-86e0089156107c60bcc49aaf8ce31d47190833b28bebb25e2aa084a7723eb0053</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttp://heart.bmj.com/content/98/23/1689.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttp://heart.bmj.com/content/98/23/1689.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>114,115,314,776,780,3183,23550,27901,27902,77342,77373</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22895643$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gassler, John P</creatorcontrib><creatorcontrib>Lynch, Petra S</creatorcontrib><creatorcontrib>Bisognano, John D</creatorcontrib><title>The role of baroreflex activation therapy in sympathetic modulation for the treatment of resistant hypertension</title><title>Heart (British Cardiac Society)</title><addtitle>Heart</addtitle><description>In comparing BAT with renal denervation, BAT requires a more involved procedure, though the second-generation system appears to be no more involved than pacemaker placement with a small lead affixed directly to the carotid sinus through a 2.5-5 cm incision. Since there is no intravascular trauma, there is no risk of secondary carotid artery stenosis occurring. [...]the BAT system can be turned off, such that in the event the patient presents with hypotension or shock, the autonomic nervous system can be allowed to respond normally to the physiologic stressor. [...]it can be adjusted upward or downward, responding to changes in the patient's overall clinical condition over the years, and can be programmed with different parameters for different therapeutic effect during day and night.</description><subject>Animals</subject><subject>Baroreflex - physiology</subject><subject>Blood pressure</subject><subject>Blood Pressure - physiology</subject><subject>Cardiac function</subject><subject>Cardiology</subject><subject>diastolic dysfunction</subject><subject>Electric Stimulation Therapy - methods</subject><subject>Heart rate</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Hypertension - physiopathology</subject><subject>Hypertension - therapy</subject><subject>hypertensive heart disease</subject><subject>Mortality</subject><subject>Nervous system</subject><subject>Physiology</subject><subject>Sympathetic Nervous System</subject><subject>systolic dysfunction</subject><subject>Veins & arteries</subject><issn>1355-6037</issn><issn>1468-201X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqNkU1v1DAQhq0K1C_6DypkiQuXtP6K7RzRCtqqq3JgQYiLZWcn2ixJHGwHdf99HaXtgRMne-xnXo3mQeiSkitKubzegQ1pP3QFI5QVnDAu5RE6pULq-ennm3znZVlIwtUJOotxTwgRlZbH6IQxXZVS8FPkNzvAwXeAfYOdDT5A08EjtnVq_9rU-gGnHQQ7HnA74HjoR5vr1Na499upW4jGh5nCKYBNPQxpDgsQ25hsLnaHEUKCIWb2HXrb2C7CxfN5jr5_-bxZ3Rbrrzd3q0_rwgkhU6ElEKIrWkpKVC2Jq2tRWdvoGjjdCkUrojl3TDtwjpXArCVaWKUYB0dIyc_RxyV3DP7PBDGZvo01dJ0dwE_RUKqollTrKqMf_kH3fgpDns5QpUmOFJJnSixUHXyMeUtmDG1vw8FQYmYh5kWImYWYRUhue_8cPrketq9NLwYyUCxAXhY8vv7b8NtIxVVpHn6szMP6Xvza3H8zM3-98K7f_98IT73PqK0</recordid><startdate>20121201</startdate><enddate>20121201</enddate><creator>Gassler, John P</creator><creator>Lynch, Petra S</creator><creator>Bisognano, John D</creator><general>BMJ Publishing Group Ltd and British Cardiovascular Society</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20121201</creationdate><title>The role of baroreflex activation therapy in sympathetic modulation for the treatment of resistant hypertension</title><author>Gassler, John P ; Lynch, Petra S ; Bisognano, John D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b446t-86e0089156107c60bcc49aaf8ce31d47190833b28bebb25e2aa084a7723eb0053</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Animals</topic><topic>Baroreflex - physiology</topic><topic>Blood pressure</topic><topic>Blood Pressure - physiology</topic><topic>Cardiac function</topic><topic>Cardiology</topic><topic>diastolic dysfunction</topic><topic>Electric Stimulation Therapy - methods</topic><topic>Heart rate</topic><topic>Humans</topic><topic>Hypertension</topic><topic>Hypertension - physiopathology</topic><topic>Hypertension - therapy</topic><topic>hypertensive heart disease</topic><topic>Mortality</topic><topic>Nervous system</topic><topic>Physiology</topic><topic>Sympathetic Nervous System</topic><topic>systolic dysfunction</topic><topic>Veins & arteries</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gassler, John P</creatorcontrib><creatorcontrib>Lynch, Petra S</creatorcontrib><creatorcontrib>Bisognano, John D</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Heart (British Cardiac Society)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gassler, John P</au><au>Lynch, Petra S</au><au>Bisognano, John D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The role of baroreflex activation therapy in sympathetic modulation for the treatment of resistant hypertension</atitle><jtitle>Heart (British Cardiac Society)</jtitle><addtitle>Heart</addtitle><date>2012-12-01</date><risdate>2012</risdate><volume>98</volume><issue>23</issue><spage>1689</spage><epage>1692</epage><pages>1689-1692</pages><issn>1355-6037</issn><eissn>1468-201X</eissn><abstract>In comparing BAT with renal denervation, BAT requires a more involved procedure, though the second-generation system appears to be no more involved than pacemaker placement with a small lead affixed directly to the carotid sinus through a 2.5-5 cm incision. 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| source | MEDLINE; BMJ Journals - NESLi2; PubMed Central |
| subjects | Animals Baroreflex - physiology Blood pressure Blood Pressure - physiology Cardiac function Cardiology diastolic dysfunction Electric Stimulation Therapy - methods Heart rate Humans Hypertension Hypertension - physiopathology Hypertension - therapy hypertensive heart disease Mortality Nervous system Physiology Sympathetic Nervous System systolic dysfunction Veins & arteries |
| title | The role of baroreflex activation therapy in sympathetic modulation for the treatment of resistant hypertension |
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